WNK1 Antibody
Referentie OAAN00903-100UL
Formaat : 100ul
Merk : Aviva Systems Biology
| Datasheets/Manuals | Printable datasheet for WNK1 Antibody (OAAN00903) |
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| Predicted Species Reactivity | Human |
|---|---|
| Product Format | Liquid |
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Application | ELISA, ICC, IF, WB |
| Reconstitution and Storage | Store at -20C. Avoid repeated freeze/thaw cycles. |
| Immunogen | WNK1 |
| Purification | Affinity purified against immunogen |
| Application Info | WB: 1:500 - 1:2,000. IHC: 1:50 - 1:200. IF: 1:50 - 1:200 |
| Gene Symbol | WNK1 |
|---|---|
| Gene Full Name | WNK lysine deficient protein kinase 1 |
| Alias Symbols | erythrocyte 65 kDa protein, HSAN2, HSN2, KDP, Kinase deficient protein, p65, PPP1R167, PRKWNK1, prostate-derived sterile 20-like kinase, Protein kinase lysine-deficient 1, protein kinase with no lysine 1, protein phosphatase 1, regulatory subunit 167, PSK, serine/threonine-protein kinase WNK1, serine/threonine-protein kinase WNK1 1, serine/threonine-protein kinase WNK1 2. |
| NCBI Gene Id | 65125 |
| Protein Name | Serine/threonine-protein kinase WNK1 |
| Description of Target | Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Activates SCNN1A, SCNN1B, SCNN1D and SGK1. Controls sodium and chloride ion transport by inhibiting the activity of WNK4, by either phosphorylating the kinase or via an interaction between WNK4 and the autoinhibitory domain of WNK1. WNK4 regulates the activity of the thiazide-sensitive Na-Cl cotransporter, SLC12A3, by phosphorylation. WNK1 may also play a role in actin cytoskeletal reorganization. Phosphorylates NEDD4L. Acts as a scaffold to inhibit SLC4A4, SLC26A6 as well as CFTR activities and surface expression, recruits STK39 which mediates the inhibition (By similarity). |
| Uniprot ID | Q9H4A3 |
| Protein Accession # | NP_001171914.1 |
| Nucleotide Accession # | NM_001184985.1 |
| Molecular Weight | 251kDa |
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What is the species homology for "WNK1 Antibody (OAAN00903)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "WNK1 Antibody (OAAN00903)"?
This item is available "Domestic: within 24 hours delivery International: 3-5 business days".
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What buffer format is "WNK1 Antibody (OAAN00903)" provided in?
This item is provided in "Liquid".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "WNK1 Antibody (OAAN00903)"?
This target may also be called "erythrocyte 65 kDa protein, HSAN2, HSN2, KDP, Kinase deficient protein, p65, PPP1R167, PRKWNK1, prostate-derived sterile 20-like kinase, Protein kinase lysine-deficient 1, protein kinase with no lysine 1, protein phosphatase 1, regulatory subunit 167, PSK, serine/threonine-protein kinase WNK1, serine/threonine-protein kinase WNK1 1, serine/threonine-protein kinase WNK1 2." in publications.
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What is the shipping cost for "WNK1 Antibody (OAAN00903)"?
The shipping cost for this item is within the US. Please contact us for specific shipping for international orders.
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What is the guarantee for "WNK1 Antibody (OAAN00903)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "WNK1 Antibody (OAAN00903)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "251kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "WNK1 Antibody (OAAN00903)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "WNK1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "WNK1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins int
