WNT8a (Protein Wnt-8a, wnt8a, wnt-8, wnt8) (AP)

Referentie MBS6460243-5x0,1mL

Formaat : 5x0.1mL

Merk : MyBiosource

WNT8a (Protein Wnt-8a, wnt8a, wnt-8, wnt8) (AP)

WNT8a Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6460243

MBS6460243 is an antibody targeting WNT8a. Also known as WNT8a (Protein Wnt-8a, wnt8a, wnt-8, wnt8) (AP). Reactive in Zebrafish. Host: Rabbit. More details

Product Overview

Online Datasheet in PDF
Product Name
WNT8a, Polyclonal Antibody
Full Product Name
WNT8a (Protein Wnt-8a, wnt8a, wnt-8, wnt8) (AP)
Product Gene Name
anti-WNT8a antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Zebrafish
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes zebrafish wnt8a. Species Crossreactivity: zebrafish
Preparation and Storage
Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
40,289 Da
3D Structure
ModBase 3D Structure for P51028
Immunogen
KLH conjugated synthetic peptide corresponding to aa135-170 at the Central region of Zebrafish wnt8a.
Conjugate
AP
Note
Preservative Free

Product Categories/Family for anti-WNT8a antibody

Antibodies; Wnt Proteins
Applications Tested/Suitable for anti-WNT8a antibody
Western Blot (WB)
Application Notes for anti-WNT8a antibody
WB: 1:1000-1:2000
Applications are based on unconjugated antibody.

Product References and Citations for anti-WNT8a antibody

Kelly G.M., et al. Development 121:1787-1799(1995). Lekven A.C., et al. Dev. Cell 1:103-114(2001).

Other Notes

Small volumes of anti-WNT8a antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for WNT8a. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
protein Wnt-8a ORF1
NCBI Official Synonym Full Names
wingless-type MMTV integration site family, member 8a
NCBI Official Symbol
wnt8a
NCBI Official Synonym Symbols
wnt8; wnt-8; wnt8.1; wu:fa20e02; wu:fe05d07
UniProt Protein Name
Protein Wnt-8a
Protein Family
Protein
UniProt Gene Name
wnt8a
UniProt Synonym Gene Names
wnt-8; wnt8
NCBI Protein Information
protein Wnt-8a ORF1

NCBI Summary for WNT8a

This gene encodes a member of the conserved Wnt family of secreted signaling proteins. The encoded protein is essential for correct patterning of the mesoderm and neural ectoderm during gastrulation. In zebrafish, two similar, functional proteins are co-transcribed from a single bicistronic mRNA. [provided by RefSeq, Apr 2013]
Show more

UniProt Comments for WNT8a

Ligand for members of the frizzled family of seven transmembrane receptors. Plays a role in embryonic patterning. May be involved in the specification of the spatial patterns of expression of Gsc and other regulatory genes leading to the establishment of the embryonic axis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-WNT8a antibody

 Products by Pathway  Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Hedgehog Signaling Pathway antibodies  Hedgehog Signaling Pathway Diagram
 Hedgehog Signaling Pathway antibodies  Hedgehog Signaling Pathway Diagram
 Melanogenesis Pathway antibodies  Melanogenesis Pathway Diagram
 Melanogenesis Pathway antibodies  Melanogenesis Pathway Diagram
 RNF Mutants Show Enhanced WNT Signaling And Proliferation Pathway antibodies  RNF Mutants Show Enhanced WNT Signaling And Proliferation Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By WNT In Cancer Pathway antibodies  Signaling By WNT In Cancer Pathway Diagram
 Signaling By Wnt Pathway antibodies  Signaling By Wnt Pathway Diagram
 TCF Dependent Signaling In Response To WNT Pathway antibodies  TCF Dependent Signaling In Response To WNT Pathway Diagram

Diseases associated with anti-WNT8a antibody

 Disease Name  Pubmed Publications
 Embryo Loss Antibodies  >14 publications with WNT8a and Embryo Loss
 Craniofacial Abnormalities Antibodies  >5 publications with WNT8a and Craniofacial Abnormalities
 Eye Abnormalities Antibodies  >4 publications with WNT8a and Eye Abnormalities
 Abnormalities, Multiple Antibodies  >3 publications with WNT8a and Abnormalities, Multiple
 Necrosis Antibodies  >3 publications with WNT8a and Necrosis
 Cardiovascular Abnormalities Antibodies  >2 publications with WNT8a and Cardiovascular Abnormalities
 Edema Antibodies  >2 publications with WNT8a and Edema
 Microcephaly Antibodies  >1 publications with WNT8a and Microcephaly
 Nervous System Malformations Antibodies  >1 publications with WNT8a and Nervous System Malformations
 Abnormalities, Drug-Induced Antibodies  >1 publications with WNT8a and Abnormalities, Drug-Induced

Organs/Tissues associated with anti-WNT8a antibody

 Organ/Tissue Name  Pubmed Publications
 Reproductive System Antibodies  >14 publications with WNT8a and Reproductive System
 Kidney Antibodies  >11 publications with WNT8a and Kidney
 Muscle Antibodies  >11 publications with WNT8a and Muscle
 Whole Body Antibodies  >4 publications with WNT8a and Whole Body