AFMID Antibody - N-terminal region
Referentie OAAB05766
Formaat : 400ul
Merk : Aviva Systems Biology
AFMID Antibody - N-terminal region (OAAB05766)
| Datasheets/Manuals | Printable datasheet for AFMID Antibody - N-terminal region (OAAB05766) |
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| Predicted Species Reactivity | Human|Mouse |
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| Product Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| Clonality | Polyclonal |
| Isotype | Rabbit Ig |
| Host | Rabbit |
| Application | FC,WB |
| Additional Information | Function: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. |
| :: | Cellular Location: Cytoplasm, cytosol. Nucleus. Note=Predominantly cytosolic. Some fraction is nuclear. |
| Reconstitution and Storage | Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Immunogen | This AFMID antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 57-83 amino acids from the N-terminal region of human AFMID. |
| Purification | This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Predicted Homology Based on Immunogen Sequence | Human; Mouse |
| Concentration | Approximately 0.5mg/ml. Actual concentration varies with each lot. |
| Application Info | WB: 1:1000 FC: 1:10~50 |
| Other Applications Image 1 Data | AFMID Antibody (N-term) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
| Gene Symbol | AFMID |
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| Alias Symbols | Arylformamidase, FKF, KF, KFA, KFase, kynurenine formamidase, N-formylkynurenine formamidase, probable arylformamidase. |
| NCBI Gene Id | 125061 |
| Protein Name | Kynurenine formamidase|kynurenine formamidase isoform 1 [Homo sapiens]|kynurenine formamidase isoform 2 [Homo sapiens] |
| Description of Target | Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. |
| Uniprot ID | Q63HM1 |
| Protein Accession # | https://www.ncbi.nlm.nih.gov/protein/NP_001010982.2,NP_001138998.1 |
| Molecular Weight | 33992 |
