Anti-LILRB1 Polyclonal Antibody
Referentie NB-64-158243-50uL
Formaat : 50uL
Merk : Neo Biotech
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Anti-LILRB1 Polyclonal Antibody
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Catalog No. TMAB-08304 Copy Product Info
Anti-LILRB1 Polyclonal Antibody is a Rabbit antibody targeting LILRB1. Anti-LILRB1 Polyclonal Antibody can be used in WB,FCM.
For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-LILRB1 Polyclonal Antibody is a Rabbit antibody targeting LILRB1. Anti-LILRB1 Polyclonal Antibody can be used in WB,FCM. |
| Ig Type | IgG |
| Reactivity | Human |
| Verified Activity | 1. Blank control (blue): Raji (fixed with 2% paraformaldehyde (10 min)). Primary Antibody: Rabbit Anti-LILRB1 antibody (TMAB-08304), Dilution: 1 μg in 100 μL 1X PBS containing 0.5% BSA; Isotype Control Antibody: Rabbit IgG (orange), used under the same conditions); Secondary Antibody: Goat anti-rabbit IgG-PE (white blue), Dilution: 1: 200 in 1 X PBS containing 0.5% BSA. 2. Sample: U937 (Human) Cell Lysate at 30 μg Primary: Anti-LILRB1 (TMAB-08304) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 72 kD Observed band size: 72 kD |
| Application | WB FCM |
| Recommended Dose | WB: 1:500-2000; FCM: 1μg/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Expressed on monocytes and B-cells, and at lower levels on dendritic cells. Detected at low levels in natural killer (NK) cells. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Immunogen | KLH conjugated synthetic peptide: human LILRB1 |
| Antigen Species | Human |
| Gene Name | LILRB1 |
| Gene ID | 10859 |
| Protein Name | Leukocyte immunoglobulin-like receptor subfamily B member 1 |
| Uniprot ID | Q8NHL6 |
| Molecular Weight | Theoretical: 72 kDa. Actual: 72 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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