• Specifications

    Product Description

    DCTN2 (Human) Cell-Based ELISA Kit is an indirect enzyme-linked immunoassay for qualitative determination of p50 Dynamitin expression in cultured cells.

    Suitable Sample

    Attached cell, loosely attached cell and suspension cell

    Label

    HRP-conjugated

    Detection Method

    Colorimetric

    Assay Type

    Qualitative

    Reactivity

    Human, Mouse, Rat

    Regulatory Status

    For research use only (RUO)

    Storage Instruction

    Store at 4°C for six months.

  • Applications

    Qualitative

  • Gene Info — DCTN2

    Entrez GeneID

    10540

    Protein Accession#

    Q13561

    Gene Name

    DCTN2

    Gene Alias

    DCTN50, DYNAMITIN, RBP50

    Gene Description

    dynactin 2 (p50)

    Omim ID

    607376

    Gene Ontology

    Hyperlink

    Gene Summary

    This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. [provided by RefSeq

    Other Designations

    50 kD dynein-associated polypeptide|dynactin 2|dynactin complex 50 kD subunit

  • Interactomes
eProcurement