Haptoglobin, Bovine Serum

Referentie MBS173105-1mg

Formaat : 1mg

Merk : MyBiosource


Haptoglobin (HPR) Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS173105

MyBioSource produces bovine serum Haptoglobin for research, life science, and manufacturing uses.Custom preparations, technical support, bulk quantities and aliquoting available.Haptoglobin can be used for the early identification of bovine respiratory… More details

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Product Overview

Product Name
Haptoglobin (HPR), Protein
Full Product Name
Haptoglobin, Bovine Serum
Product Gene Name
HPR protein
Product Synonym Names
Haptoglobin (Hp), Bovine
Form/Format
Frozen solution in phosphate buffered saline with 0.05% sodium azide
Purity/Purification
> or = 90% (SDS-PAGE, bands at 10 and 40kDa indicative of alpha and beta subunits)
Preparation and Storage
At -20 degree C. Avoid freeze/thaws.
Shipping: Ships with dry ice
Molecular Weight
623.65
OMIM
140210
Source
Bovine acute phase serum
Protein
0.93 mg/ml (E1mg/ml280nm=1.68
Note
Due to high affinity for hemoglobin, haptoglobin preparations unavoidably contain hemoglobin, which co-purifies during all chromatographic steps.
Handling
Handle as a potentially hazardous substance.
Recovery
Centrifuge briefly to ensure complete recovery. Mix thoroughly before sampling.

Product Categories/Family for HPR protein

Other Notes

Small volumes of HPR protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HPR purchase

MBS173105 is a protein targeting HPR. Also known as Haptoglobin, Bovine Serum.

Additional Details

NCBI/Uniprot data below describe general gene information for HPR. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
haptoglobin, partial
NCBI Official Synonym Full Names
haptoglobin-related protein
NCBI Official Symbol
HPR
NCBI Official Synonym Symbols
HP; A-259H10.2
UniProt Protein Name
Haptoglobin-related protein
Protein Family
Glycerate dehydrogenase
UniProt Gene Name
HPR
UniProt Entry Name
HPTR_HUMAN
NCBI Protein Information
haptoglobin-related protein; Haptoglobin-related locus

NCBI Summary for HPR

This gene encodes a haptoglobin-related protein that binds hemoglobin as efficiently as haptoglobin. Unlike haptoglobin, plasma concentration of this protein is unaffected in patients with sickle cell anemia and extensive intravascular hemolysis, suggesting a difference in binding between haptoglobin-hemoglobin and haptoglobin-related protein-hemoglobin complexes to CD163, the hemoglobin scavenger receptor. This protein may also be a clinically important predictor of recurrence of breast cancer. [provided by RefSeq, Oct 2011]
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UniProt Comments for HPR

HPR: a haptoglobin-related protein that binds hemoglobin as efficiently as haptoglobin. Unlike haptoglobin, plasma concentration of this protein is unaffected in patients with sickle cell anemia and extensive intravascular hemolysis, suggesting a difference in binding between haptoglobin-hemoglobin and haptoglobin-related protein-hemoglobin complexes to CD163, the hemoglobin scavenger receptor. This protein may also be a clinically important predictor of recurrence of breast cancer. [provided by RefSeq, Oct 2011]

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 16q22.1

Cellular Component: extracellular region

Molecular Function: hemoglobin binding; catalytic activity

Biological Process: receptor-mediated endocytosis; metabolic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with HPR protein

 Reference Product  PubMed Publications
 HBD protein  >4 publications with HPR and HBD
 APOA1 protein  >3 publications with HPR and APOA1
 ASGR1 protein  >1 publications with HPR and ASGR1
 IL6 protein  >1 publications with HPR and IL6

Pathways associated with HPR protein

 Products by Pathway  Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 Binding And Uptake Of Ligands By Scavenger Receptors Pathway antibodies  Binding And Uptake Of Ligands By Scavenger Receptors Pathway Diagram
 Scavenging Of Heme From Plasma Pathway antibodies  Scavenging Of Heme From Plasma Pathway Diagram

Diseases associated with HPR protein

 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >122 publications with HPR and Breast Neoplasms
 Neoplasms, Experimental Antibodies  >92 publications with HPR and Neoplasms, Experimental
 Heart Diseases Antibodies  >80 publications with HPR and Heart Diseases
 Mammary Neoplasms, Animal Antibodies  >44 publications with HPR and Mammary Neoplasms, Animal
 Ovarian Neoplasms Antibodies  >37 publications with HPR and Ovarian Neoplasms
 Kidney Diseases Antibodies  >35 publications with HPR and Kidney Diseases
 Immune System Diseases Antibodies  >30 publications with HPR and Immune System Diseases
 Liver Neoplasms Antibodies  >24 publications with HPR and Liver Neoplasms
 Cell Transformation, Neoplastic Antibodies  >21 publications with HPR and Cell Transformation, Neoplastic
 Inflammation Antibodies  >21 publications with HPR and Inflammation

Organs/Tissues associated with HPR protein

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >78 publications with HPR and Liver
 Brain Antibodies  >52 publications with HPR and Brain
 Heart Antibodies  >51 publications with HPR and Heart
 Lung Antibodies  >50 publications with HPR and Lung