IL1 Receptor 1 antibody
Referentie GTX22575-500ul
Formaat : 500ul
Merk : Genetex
Host | Rabbit |
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Clonality | Polyclonal |
Isotype | IgG |
Application | WB, FACS, IP, ELISA, IHC, Neutralizing/Inhibition |
Reactivity | Human, Primate |
Package | 500 μl |
View product citations for antibody GTX22575 on CiteAb
APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application | Recommended Dilution |
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WB | Assay dependent |
FACS | Assay dependent |
IP | Assay dependent |
ELISA | Assay dependent |
IHC | Assay dependent |
Neutralizing/Inhibition | Assay dependent |
Not tested in other applications.
Calculated MW
65 kDa. ( Note )
Product Note
The antiserum is directed against the extracellular domain of the human IL-1R type I, but precipitates the intact receptor expressed on human cells. The antibody does not recognize human IL-1, IL-1Ra or IL-1R type II. In ELISA formats and other immunoreactive assays, this antibody will detect the extracellular domain of the IL-1R type I (also called soluble IL-1R type I or ''decoy'' receptor) found in human body fluids, particularly in the circulation, urine and supernatants of cells and synovial fluid.
PROPERTIES
Form
Liquid
Buffer
10mM Sodium Phosphate, 150mM NaCl
Preservative
0.01% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
84 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant human IL-1R type I.
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
interleukin 1 receptor type 1 , CD121A , D2S1473 , IL-1R-alpha , IL1R , IL1RA , P80
Cellular Localization
Membrane,Cell membrane,Secreted
Background
Interleukin 1 (IL-1), which has a role as a mediator in inflammation, actually consists of 2 separate but related proteins, IL-1 alpha and IL-1 beta. Cell surface receptors for the 2 forms of IL-1 are identical. IL-1R Type I contains a single membrane-spanning segment, a large cytoplasmic region, and an extracellular, IL-1 binding portion composed of 3 immunoglobulin-like domains.
Database
REVIEW
SDS | |
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Sodium Azide.pdf |