Orb1220847-1g | Nerol [106-25-2] Clinisciences

Nerol

SKU: orb1220847

Description

Nerol is a monoterpene found in many essential oils such as lemon balm and hop.Nerol can lessened the severity of ouabain-triggered arrhythmias in mammalian heart.

Images & Validation

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Key Properties

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CAS Number	106-25-2
MW	154.25
Purity	>98% (HPLC)
Formula	C₁₀H₁₈O
SMILES	C\C(C)=C\CC\C(C)=C/CO
Target	Others
Solubility	In Vitro: DMSO : ≥ 100 mg/mL (648.30 mM)

Bioactivity

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In Vitro	Nerol induces apoptosis associated with the generation of ROS and Ca2+ overload in saprotrophic fungus Aspergillus flavus. The antifungal activity of Nerol (NEL) against Candida albicans, a pathogenic fungus, has a minimum inhibitory concentration (MIC) of 4.4 μM that causes noteworthy candidacidal activity through an apoptosis-like mechanism. Nerol triggers mitochondrial dysfunction and disruption via elevation of Ca2+ and ROS in Candida albicans.

In Vitro

Nerol induces apoptosis associated with the generation of ROS and Ca2+ overload in saprotrophic fungus Aspergillus flavus. The antifungal activity of Nerol (NEL) against Candida albicans, a pathogenic fungus, has a minimum inhibitory concentration (MIC) of 4.4 μM that causes noteworthy candidacidal activity through an apoptosis-like mechanism. Nerol triggers mitochondrial dysfunction and disruption via elevation of Ca2+ and ROS in Candida albicans.

Storage & Handling

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Storage	Storage temperature: -20°C. Stability: ≥ 2 years
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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Cis-Geraniol | Neryl alcohol

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Neryl acetate [orb1297730]
Purity:
97.15% (May vary between batches)
CAS Number:
141-12-8
MW:
196.29
Formula:
C₁₂H₂₀O₂
Sizes Available: 1 ml x 10 mM (in DMSO)
Nerol [orb1301624]
Purity:
98.59% (May vary between batches)
CAS Number:
106-25-2
MW:
154.25
Formula:
C₁₀H₁₈O
Sizes Available: 500 mg, 1 ml x 10 mM (in DMSO), 5 g, 1 g

Quick Database Links

Gene Symbol

Others

Nerol [106-25-2]

Referentie orb1220847-1g

Merk : Biorbyt