Clinisciences > AIF1 Antibody
AIF1 Antibody
Referentie OAGA01616
Formaat : 100ul
Merk : Aviva Systems Biology
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| Datasheets/Manuals | Printable datasheet for AIF1 Antibody (OAGA01616) |
|---|
| Predicted Species Reactivity | Human|Mouse|Rat |
|---|---|
| Product Format | Liquid |
| Clonality | Polyclonal |
| Isotype | IgG |
| Host | Rabbit |
| Conjugation | Unconjugated |
| Application | FACS|ICC|IF|IHC|IHC-Fr|IHC-P|IP|WB |
| :: | Positive Controls: THP-1, HL-60, mouse liver, rat liver |
| Reconstitution and Storage | -20°C or -80°C|2°C to 8°C |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human Iba1. The exact sequence is proprietary. |
| Purification | Affinity Purified |
| Predicted Homology Based on Immunogen Sequence | Pig (93%), Rhesus Monkey (99%), Bovine (88%) |
| Concentration | 0.14 mg/ml |
| Application Info | WB: 1:500~10000 FACS: 1:50~200 ICC/IF: 1:100~1000 IHC-F: 1:100~1000 IHC-FFPE: 1:100~1000 IP: 1:100~500 |
| Gene Symbol | AIF1 |
|---|---|
| Gene Full Name | allograft inflammatory factor 1 |
| Alias Symbols | AIF-1, allograft inflammatory factor 1, IBA1, interferon gamma responsive transcript, ionized calcium-binding adapter molecule 1, IRT-1, IRT1, protein G1. |
| NCBI Gene Id | 199 |
| Protein Name | Allograft inflammatory factor 1 |
| Description of Target | Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation. |
| Uniprot ID | P55008 |
| Molecular Weight | 17 kDa |
Protein interactions
| Name | # of Products |
|---|---|
| ACTA1 | 271 |
| LCP1 | 15 |
Biological pathways
| Name | # of Products |
|---|---|
| Actin filament bundle assembly | 30 |
| Cell cycle arrest | 360 |
| Inflammatory response | 911 |
| Negative regulation of cell proliferation | 554 |
Biological process
| Name | # of Products |
|---|---|
| Actin filament bundle assembly | 23 |
| Cell cycle arrest | 142 |
| Cellular response to chemical stimulus | 4 |
| Cellular response to extracellular stimulus | 17 |
| Cellular response to hormone stimulus | 35 |
| Inflammatory response | 339 |
| Negative regulation of apoptotic process | 356 |
| Negative regulation of cell proliferation | 375 |
| Negative regulation of gene expression | 70 |
| Positive regulation of cell migration | 150 |
| Positive regulation of muscle hyperplasia | 1 |
| Positive regulation of nitric oxide biosynthetic process | 53 |
| Positive regulation of protein phosphorylation | 125 |
| Positive regulation of smooth muscle cell proliferation | 67 |
| Response to axon injury | 34 |
| Response to cytokine stimulus | 73 |
| Response to electrical stimulus | 23 |
| Response to stress | 160 |
Cellular components
| Name | # of Products |
|---|---|
| Actin filament | 25 |
| Cytoplasm | 4549 |
| Cytoskeleton | 630 |
| Cytosol | 1868 |
| Lamellipodium | 74 |
| Nucleus | 4914 |
| Perikaryon | 44 |
| Phagocytic cup | 11 |
| Plasma membrane | 2678 |
| Ruffle | 62 |
| Ruffle membrane | 39 |
Protein function
| Name | # of Products |
|---|---|
| Actin filament binding | 152 |
| Calcium ion binding | 1062 |
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Goat Anti-AIF1 / IBA1 (isoform 1 and 3) Antibody (OAEB01061)Catalog #: OAEB01061Species Tested: Human, Mouse, RatApplication: ELISA|IHC|WBFormat: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. -
Goat Anti-AIF1 / IBA1 (isoform 3) Antibody (OAEB02397)Catalog #: OAEB02397Application: ELISA|FC|IF|IHCFormat: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. -
AIF1 Antibody (OAGA00004)Catalog #: OAGA00004Conjugation: UnconjugatedApplication: FACS|ICC|IF|IHC|IHC-Flt|IHC-Fr|IHC-P|WBFormat: Liquid -
AIF1 Antibody (OABF00661)Catalog #: OABF00661Conjugation: UnconjugatedApplication: ELISA, FC, ICC, IF, IHC-Fr, IHC-P, WBFormat: Liquid. Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. -
AIF1 Recombinant Protein (Rat) (OPCA01455)Catalog #: OPCA01455Format: Liquid or Lyophilized powder


