Anti-Mouse IFN gamma Antibody (XMG1.2)

Anti-Mouse IFN gamma Antibody (XMG1.2) is an inhibitory antibody that targets and neutralizes mouse IFN-γ, suitable for research in cancer, inflammation, and immunology.

Anti-Mouse IFN gamma Antibody (XMG1.2) (500 μg; intraperitoneal injection; administered on days 0/3/7/10/14/17) increased the incidence and severity of multiple myeloma in a mouse model, indicating IFNγ as a mediator of successful anti-myeloma immune responses in the 5TGM1 metastasis model [1].
Anti-Mouse IFN gamma Antibody (XMG1.2) is effective in a mouse model of hemophagocytic lymphohistiocytosis secondary to chronic inflammation [2].
Anti-Mouse IFN gamma Antibody (XMG1.2) (100 mg/kg; intravenous injection; administered on days 14/20/28/35/42) improved graft implantation in Ifngr1-/- mice infected with BCG [3].
Anti-Mouse IFN gamma Antibody (XMG1.2) (100 μg; intraperitoneal injection; administered every other day starting on day 10) prevented Purkinje cell loss and clinical disease in a mouse model of paraneoplastic cerebellar degeneration [4].
Anti-Mouse IFN gamma Antibody (XMG1.2) (100 µg/g; intraperitoneal injection; single dose) increased survival in an LPS-induced macrophage activation syndrome mouse model[5].
Anti-Mouse IFN gamma Antibody (XMG1.2) (500 μg; intraperitoneal injection; administered on days 0/3/7/10/14/17) increased the incidence and severity of multiple myeloma in a mouse model, indicating IFNγ as a mediator of successful anti-myeloma immune responses in the 5TGM1 metastasis model [1].
Anti-Mouse IFN gamma Antibody (XMG1.2) is effective in a mouse model of hemophagocytic lymphohistiocytosis secondary to chronic inflammation [2].
Anti-Mouse IFN gamma Antibody (XMG1.2) (100 mg/kg; intravenous injection; administered on days 14/20/28/35/42) improved graft implantation in Ifngr1-/- mice infected with BCG [3].
Anti-Mouse IFN gamma Antibody (XMG1.2) (100 μg; intraperitoneal injection; administered every other day starting on day 10) prevented Purkinje cell loss and clinical disease in a mouse model of paraneoplastic cerebellar degeneration [4].
Anti-Mouse IFN gamma Antibody (XMG1.2) (100 µg/g; intraperitoneal injection; single dose) increased survival in an LPS-induced macrophage activation syndrome mouse model[5].

XMG1.2

Mouse

Monoclonal

Unconjugated