BACE2 Polyclonal Antibody, Biotin Conjugated
Referentie bs-10494R-Biotin
Formaat : 100uL
Merk : Bioss
Applications
Predicted Reactivity
| Overview | |
| Catalog # | bs-10494R-Biotin |
| Product Name | BACE2 Polyclonal Antibody, Biotin Conjugated |
| Applications | ELISA, IHC-P, IHC-F |
| Predicted Reactivity | Human, Mouse, Rat, Dog, Cow, Sheep, Pig |
| Specifications | |
| Conjugation | Biotin |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human BACE2 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C for 12 months. |
| Target | |
| Gene ID | 25825 |
| Swiss Prot | Q9Y5Z0 |
| Subcellular location | Cell membrane |
| Synonyms | ASP1; BAE2; DRAP; AEPLC; ALP56; ASP21; CDA13; CEAP1; Beta-secretase 2; Aspartic-like protease 56 kDa; Aspartyl protease 1; Asp 1; Beta-site amyloid precursor protein cleaving enzyme 2; Beta-site APP cleaving enzyme 2; Down region aspartic protease; Memapsin-1; Membrane-associated aspartic protease 1; Theta-secretase; BACE2; UNQ418/PRO852 |
| Background | Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. It has also been shown that it can cleave APP between residues 671 and 672. |
| Application Dilution | |
| ELISA | 1:500-1000 |
| IHC-P | 1:200-400 |
| IHC-F | 1:100-500 |