Cannabinoid Receptor I (CNR1) Goat Polyclonal Antibody

Referentie TA302439

Formaat : 100ug


Cannabinoid Receptor I (CNR1) Goat Polyclonal Antibody

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SKU
TA302439
Goat Polyclonal Antibody against Cannabinoid Receptor 1
 
Specifications
Product Data
Application WB
Recommended Dilution ELISA: 1:32,000. WB: 1-3µg/ml.
Reactivity Dog), Human, Mouse (Expected from sequence similarity: Rat
Antibody Host Goat
Isotype IgG
Clonality Polyclonal
Immunogen Peptide with sequence C-HTSEDGKVQVTRPDQ, from the internal region of the protein sequence according to NP_057167.2; NP_149421.1.
Buffer Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration lot specific
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 49501 Da
Gene Name cannabinoid receptor 1 (brain)
Database Link
Background This gene encodes a protein that is one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the family of guanine-nucleotide-binding protein (G-protein) coupled receptors which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Two transcript variants encoding different isoforms have been described for this gene. provided by RefSeq
Synonyms CANN6; CB-R; CB1; CB1A; CB1K5; CB1R; CNR
Reference Data
Protein Categories GPCR, Intracellular Proteins, Membrane Proteins
Protein Families Druggable Genome, GPCR, Transmembrane
Protein Pathways Neuroactive ligand-receptor interaction

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