Exportin 5 Recombinant Antibody, Biotin Conjugated
Referentie bsm-61945R-Biotin
Formaat : 100uL
Merk : Bioss
Applications
Reactivity
| Overview | |
| Catalog # | bsm-61945r-biotin |
| Product Name | Exportin 5 Recombinant Antibody, Biotin Conjugated |
| Applications | WB, IHC-P, IHC-F |
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Biotin |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human Exportin 5 |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | Lot dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 57510 |
| Swiss Prot | Q9HAV4 |
| Subcellular location | Cytoplasm, Nucleus |
| Synonyms | Exp5; Exportin 5; Ranbp21; xpo5. |
| Background | E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.Interacts with SMAD7 to trigger SMAD7-mediated transforming growth factor beta/TGF-beta receptor ubiquitin-dependent degradation, thereby down-regulating TGF-beta signaling. |
| Application Dilution | |
| WB | 1:500-2000 |
| IHC-P | IHC-P1:100-200 |
| IHC-F | IHC-F1:100-200 |