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> GAD67 (GAD1) Mouse Monoclonal Antibody [Clone ID: OTI3H2]

GAD67 (GAD1) Mouse Monoclonal Antibody [Clone ID: OTI3H2]

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Referentie TA500328S

Formaat : 30ul


GAD67 (GAD1) Mouse Monoclonal Antibody [Clone ID: OTI3H2]

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SKU
TA500328S
GAD1 (GAD67) mouse monoclonal antibody, clone OTI3H2 (formerly 3H2)
Size:
30 ul 100 ul
Conjugation:
Unconjugated
 

View other "GAD67 or NM_000817" antibodies

Specifications
Product Data
Clone Name OTI3H2
Application IF, IHC, IP, WB
Recommended Dilution WB 1:500-1:1000, IHC 1:50, IF 1:100, IP: 4ug/mL
Reactivity Dog, Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Full length human recombinant protein of human GAD1 (NP_000808) produced in HEK293T cell.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 0.46 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 66.9 kDa
Gene Name glutamate decarboxylase 1
Database Link
Background This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form.
Synonyms CPSQ1; DEE89; GAD; SCP
Reference Data
Protein Categories Intracellular Proteins, Nervous system Diseases
Protein Families Druggable Genome
Protein Pathways Alanine, aspartate and glutamate metabolism, beta-Alanine metabolism, Butanoate metabolism, Metabolic pathways, Taurine and hypotaurine metabolism, Type I diabetes mellitus
Product Manuals
FAQs
  • Antibody and Western Standard
SDS
SKU Description Size
CF500328 Carrier-free (BSA/glycerol-free) GAD1 mouse monoclonal antibody, clone OTI3H2 (formerly 3H2) 100 ug
TA500328 GAD1 (GAD67) mouse monoclonal antibody, clone OTI3H2 (formerly 3H2) 100 ul
TA500328AM GAD1 (GAD67) mouse monoclonal antibody, clone OTI3H2 (formerly 3H2), Biotinylated 100 ul
TA500328BM GAD1 (GAD67) mouse monoclonal antibody, clone OTI3H2 (formerly 3H2), HRP conjugated 100 ul

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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