Human Myelin-oligodendrocyte glycoprotein, MOG ELISA Kit
Referentie MBS928110-96
Formaat : 96-Strip-Wells
Merk : MyBiosource
Myelin Oligodendrocyte Glyco (MOG) ELISA Kit for Human
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS928110Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for MOG has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any MOG present is bound by the… More details
Product Overview
Product Name
myelin oligodendrocyte glycoprotein (MOG), ELISA Kit
Full Product Name
Human Myelin-oligodendrocyte glycoprotein, MOG ELISA Kit
Product Gene Name
MOG elisa kit
Product Synonym Names
Human Myelin-oligodendrocyte glycoprotein (MOG) ELISA kit; DAQB-92E24.2; MGC26137; MOGIG2; MOG Ig-AluB; myelin oligodendrocyte glycoprotein
Species Reactivity
Human
Assay Type
Quantitative Sandwich
Samples
Serum, plasma, tissue homogenates
Detection Range
15.6 pg/ml-1000 pg/ml
Sensitivity
< 3.9 pg/ml
Specificity
This assay has high sensitivity and excellent specificity for detection of human MOG. No significant cross-reactivity or interference between human MOG and analogues was observed.
Preparation and Storage
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
Inter-assay Precision
Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
Intra-assay Precision
Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess.
Molecular Weight
28,193 Da
OMIM
gene 614250
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of MOG elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for MOG purchase
MBS928110 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the myelin oligodendrocyte glycoprotein (MOG) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing MOG. The ELISA analytical biochemical technique of the MBS928110 kit is based on MOG antibody-MOG antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect MOG antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, MOG. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Additional Details
NCBI/Uniprot data below describe general gene information for MOG. It may not necessarily be applicable to this product.
NCBI Official Full Name
myelin-oligodendrocyte glycoprotein isoform alpha3
NCBI Official Synonym Full Names
myelin oligodendrocyte glycoprotein
NCBI Official Symbol
MOG
NCBI Official Synonym Symbols
BTN6; BTNL11; MOGIG2; NRCLP7
UniProt Protein Name
Myelin-oligodendrocyte glycoprotein
Protein Family
Molybdopterin adenylyltransferase
UniProt Gene Name
MOG
UniProt Entry Name
MOG_HUMAN
NCBI Protein Information
myelin-oligodendrocyte glycoprotein; MOG Ig-AluB; MOG alpha-5
NCBI Summary for MOG
The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Show more UniProt Comments for MOG
MOG: Mediates homophilic cell-cell adhesion. Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell- cell communication. Defects in MOG are the cause of narcolepsy type 7 (NRCLP7). Neurological disabling sleep disorder, characterized by excessive daytime sleepiness, sleep fragmentation, symptoms of abnormal rapid-eye-movement (REM) sleep, cataplexy, hypnagogic hallucinations, and sleep paralysis. Cataplexy is a sudden loss of muscle tone triggered by emotions, which is the most valuable clinical feature used to diagnose narcolepsy. Human narcolepsy is primarily a sporadically occurring disorder but familial clustering has been observed. Belongs to the immunoglobulin superfamily. BTN/MOG family. 10 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 6p22.1
Cellular Component: plasma membrane; integral to membrane
Biological Process: central nervous system development; positive regulation of MyD88-dependent toll-like receptor signaling pathway; cell adhesion
Disease: Narcolepsy 7
Show more Protein type: Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 6p22.1
Cellular Component: plasma membrane; integral to membrane
Biological Process: central nervous system development; positive regulation of MyD88-dependent toll-like receptor signaling pathway; cell adhesion
Disease: Narcolepsy 7
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Diseases associated with MOG elisa kit
| Disease Name | Pubmed Publications |
|---|---|
| Nervous System Diseases Antibodies | >878 publications with MOG and Nervous System Diseases |
| Encephalomyelitis, Autoimmune, Experimental Antibodies | >713 publications with MOG and Encephalomyelitis, Autoimmune, Experimental |
| Brain Diseases Antibodies | >703 publications with MOG and Brain Diseases |
| Inflammation Antibodies | >261 publications with MOG and Inflammation |
| Necrosis Antibodies | >82 publications with MOG and Necrosis |
| Drug Toxicity Antibodies | >42 publications with MOG and Drug Toxicity |
| Neoplasms Antibodies | >32 publications with MOG and Neoplasms |
| Nerve Degeneration Antibodies | >28 publications with MOG and Nerve Degeneration |
| Mental Disorders Antibodies | >25 publications with MOG and Mental Disorders |
| Vascular Diseases Antibodies | >15 publications with MOG and Vascular Diseases |
Organs/Tissues associated with MOG elisa kit
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Brain Antibodies | >355 publications with MOG and Brain |
| Spinal Cord Antibodies | >256 publications with MOG and Spinal Cord |
| Kidney Antibodies | >9 publications with MOG and Kidney |
| Intestine Antibodies | >7 publications with MOG and Intestine |
| Heart Antibodies | >3 publications with MOG and Heart |
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