Integrin alpha 5 Recombinant Antibody, APC-Cy7 Conjugated
Referentie bsm-61357R-APC-Cy7
Formaat : 100uL
Merk : Bioss
Applications
Reactivity
| Overview | |
| Catalog # | bsm-61357r-apc-cy7 |
| Product Name | Integrin alpha 5 Recombinant Antibody, APC-Cy7 Conjugated |
| Applications | WB, IF(IHC-P) |
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | APC-Cy7 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human Integrin alpha 5 |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | Lot dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 3678 |
| Swiss Prot | P08648 |
| Subcellular location | Cell membrane |
| Synonyms | Integrin alpha-5; VLA-5; CD49e; ITGA5; FNRA. |
| Background | Integrin alpha-5/beta-1 (ITGA5:ITGB1) is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. ITGA5:ITGB1 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1. |
| Application Dilution | |
| WB | 1:500-2000 |
| IF(IHC-P) | IFIHC-P1:50-200 |

