General Info
| Applications: | ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 0.065ng/mL |
| Detection Limit: | 0.156-10ng/mL |
| Short Description: | This SFRP4 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 4.5 hrs |
Information
| Gene Symbol: | Sfrp4 |
| Gene ID: | 20379 |
| Uniprot ID: | SFRP4_MOUSE |
| Sample Type: | serum, plasma or other biological fluids. |
Description
| Tissue Specificity | Expressed in the ovary. Localized to granulosa cells of periovulatory follicles and corpora lutea. Weakly expressed in adult tissues including kidney, brain and lung. |
| Post Translational Modifications | |
| Function | Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP4 plays a role in bone morphogenesis. May also act as a regulator of adult uterine morphology and function. May also increase apoptosis during ovulation possibly through modulation of FZ1/FZ4/WNT4 signaling. Has phosphaturic effects by specifically inhibiting sodium-dependent phosphate uptake. |
| Protein Name | Secreted Frizzled-Related Sequence Protein 4Frp-4Sfrp-4 |
| Database Links | |
| Cellular Localisation | Secreted |
| Alternative ELISA Names | Secreted Frizzled-Related Sequence Protein 4 ELISA kitFrp-4 ELISA kitSfrp-4 ELISA kitSfrp4 ELISA kit |
| output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance