Reagentia en instrumenten voor immunologie, celbiologie en moleculaire biologie.
 
> Presenilin 1 (PSEN1) Human shRNA Plasmid Kit (Locus ID 5663)

Presenilin 1 (PSEN1) Human shRNA Plasmid Kit (Locus ID 5663)

Afdrukken Afdrukken
Log in alstublieft

Referentie TL320496

Formaat : 1kit


Presenilin 1 (PSEN1) Human shRNA Plasmid Kit (Locus ID 5663)

Be the first to review this product
SKU
TL320496
PSEN1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
 

Other products for "Presenilin 1 or NM_000021"

Specifications
Product Data
Locus ID 5663
Synonyms ACNINV3; AD3; FAD; PS-1; PS1; S182
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components PSEN1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 5663). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_000021, NM_007318, NM_007319, NM_000021.1, NM_000021.2, NM_000021.3, NM_007318.1, NM_007318.2, BC011729, BC002708, NM_000021.4, NM_007318.3
UniProt ID P49768
Summary Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1; PSEN2) or in the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP. Also, it is thought that the presenilins are involved in the cleavage of the Notch receptor, such that they either directly regulate gamma-secretase activity or themselves are protease enzymes. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene, the full-length nature of only some have been determined. provided by RefSeq, Aug 2008
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact tech@clinisciences.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
Product Manuals
FAQs
  • shRNA (HuSH-29)
SDS

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products

Misschien heeft u ook interesse in de volgende producten:



Referentie
Beschrijving
Cond.
Price Bef. VAT