Protease, Human Pancreas

Protease, Human Pancreas
Catalog number: B2019159
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 0.1 mg
Molecular Weight or Concentration: 25,000 g/mol
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: −20°C
Keywords: Protease, Human Pancreas
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Mayerle J, Sendler M, Hegyi E, Beyer G, Lerch MM, Sahin-Tóth M. Genetics, Cell Biology, and Pathophysiology of Pancreatitis Gastroenterology. 2019 May;156(7):1951-1968.e1.
2: Whitcomb DC, Lowe ME. Human pancreatic digestive enzymes Dig Dis Sci. 2007 Jan;52(1):1-17.
3: Hayakawa T, Naruse S, Kitagawa M, Kondo T. [Elastase] Nihon Rinsho. 1995 May;53(5):1192-7.
4: Müller JA, Groß R, Conzelmann C, Krüger J, Merle U, Steinhart J, Weil T, Koepke L, Bozzo CP, Read C, Fois G, Eiseler T, Gehrmann J, van Vuuren J, Wessbecher IM, Frick M, Costa IG, Breunig M, Grüner B, Peters L, Schuster M, Liebau S, Seufferlein T, Stenger S, Stenzinger A, MacDonald PE, Kirchhoff F, Sparrer KMJ, Walther P, Lickert H, Barth TFE, Wagner M, Münch J, Heller S, Kleger A. SARS-CoV-2 infects and replicates in cells of the human endocrine and exocrine pancreas Nat Metab. 2021 Feb;3(2):149-165.
5: Suhaj P, Olejar T, Matej R. PAR2: The Cornerstone of Pancreatic Diseases Physiol Res. 2022 Nov 28;71(5):583-596.
6: Khiatah B, Tucker A, Chen KT, Perez R, Bilbao S, Valiente L, Medrano L, Rawson J, Forouhar E, Omori K, Kandeel F, Qi M, Al-Abdullah IH. Evaluation of collagenase gold plus BP protease in isolating islets from human pancreata Islets. 2018 Mar 4;10(2):51-59.
7: Brandhorst H, Johnson PR, Mönch J, Kurfürst M, Korsgren O, Brandhorst D. Comparison of Clostripain and Neutral Protease as Supplementary Enzymes for Human Islet Isolation Cell Transplant. 2019 Feb;28(2):176-184.
8: Mallory PA, Travis J. Human pancreatic enzymes: purification and characterization of a nonelastolytic enzyme, protease E. resembling elastase Biochemistry. 1975 Feb 25;14(4):722-30.
9: Cariou B, Si-Tayeb K, Le May C. Role of PCSK9 beyond liver involvement Curr Opin Lipidol. 2015 Jun;26(3):155-61.
https://pubmed.ncbi.nlm.nih.gov/12605110

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