Recombinant Bovine G protein-coupled receptor 161 (GPR161)
Referentie MBS7016128-0,1mg
Formaat : 0.1mg
Merk : MyBiosource
G Protein-Coupled Receptor 161 (GPR161) Bovine Recombinant Protein
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS7016128MBS7016128 is a recombinant protein targeting GPR161. Also known as Recombinant Bovine G protein-coupled receptor 161 (GPR161). Host: Cell Free Expression. More details
Product Overview
Product Name
G protein-coupled receptor 161 (GPR161), Recombinant Protein
Full Product Name
Recombinant Bovine G protein-coupled receptor 161 (GPR161)
Product Gene Name
GPR161 recombinant protein
Sequence
MSLNSSLGHR KELSNLTEGA SDQGGSGVTE FVAIVIITVF VCLGNLVIVI TLYRKSYLLT LSNKFVFSLT LSNFLLSVLV LPFVVTSSIR REWIFGVVWC NFSALLYLLI SSASMLTLGI IAVDRYYAVL YPMAYPMKIT GNRAVMVLAY IWLHSLIGCL PPLFGWSSVE FDEFKWMCVA AWHREPGYTA FWQIWCALLP FLVMLVCYGF IFRVARVKAR KVHCGAVVTV EVGVQRTGRK NSSTSTSSSG SRKSAFQGVV YSANQCKALV TILVVIGAFM VTWGPYMVVI TSEALWGKNC VSPTLETWAT WLSFTSAICH PLIYGLWNKT VRKELLGMCF GDRYYREPFV QRQRTSRLFS ISNRITDLGL SPHLTALMAG EQPLGNSSST GDTGFSCSQD SGTDVMLLED YTSDDNPLHG TCPPKRRSSV TFEDEVEQIK EAAKNPILHV KADVHKSLDS YATSLAKAIE AEAKINLFGE EALPGVLLTA RTVPGIGFGS RRGSRTLAGQ RLQLQSIEEG DVLATEQR
Host
Cell Free Expression
Form/Format
Liquid containing glycerol
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
Molecular Weight
58,349 Da
Sequence Positions
1-528aa; full length protein
Species
Bovine
Product Categories/Family for GPR161 recombinant protein
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Application Notes for GPR161 recombinant protein
This is a recombinant transmembrane protein expressed in a cell-free expression system.
Other Notes
Small volumes of GPR161 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for GPR161. It may not necessarily be applicable to this product.
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
G protein-coupled receptor 161
NCBI Official Symbol
GPR161
UniProt Protein Name
G protein-coupled receptor 161
Protein Family
G protein-coupled receptor
UniProt Gene Name
GPR161
UniProt Entry Name
GP161_BOVIN
NCBI Protein Information
G protein-coupled receptor 161
UniProt Comments for GPR161
Key negative regulator of Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development. Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of GLI3 into GLI3R and repress the Shh signaling. In presence of SHH, it is removed from primary cilia and is internalized into recycling endosomes, preventing its activity and allowing activation of the Shh signaling. Its ligand is unknown ().
Show more Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Pathways associated with GPR161 recombinant protein
| Products by Pathway | Pathway Diagram |
|---|---|
| GPCRs, Class A Rhodopsin-like Pathway antibodies | GPCRs, Class A Rhodopsin-like Pathway Diagram |
| Hedgehog 'off' State Pathway antibodies | Hedgehog 'off' State Pathway Diagram |
| Hedgehog 'on' State Pathway antibodies | Hedgehog 'on' State Pathway Diagram |
| Signal Transduction Pathway antibodies | Signal Transduction Pathway Diagram |
| Signaling By Hedgehog Pathway antibodies | Signaling By Hedgehog Pathway Diagram |
Diseases associated with GPR161 recombinant protein
| Disease Name | Pubmed Publications |
|---|---|
| Congenital Abnormalities Antibodies | >5 publications with GPR161 and Congenital Abnormalities |
| Breast Neoplasms Antibodies | >1 publications with GPR161 and Breast Neoplasms |
| Abnormalities, Multiple Antibodies | >1 publications with GPR161 and Abnormalities, Multiple |
| Kidney Diseases Antibodies | >1 publications with GPR161 and Kidney Diseases |
| Inflammation Antibodies | >1 publications with GPR161 and Inflammation |
| Disease Models, Animal Antibodies | >1 publications with GPR161 and Disease Models, Animal |
| Neurobehavioral Manifestations Antibodies | >1 publications with GPR161 and Neurobehavioral Manifestations |
| Necrosis Antibodies | >1 publications with GPR161 and Necrosis |
Organs/Tissues associated with GPR161 recombinant protein
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Brain Antibodies | >2 publications with GPR161 and Brain |