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> β-D-Glucan [9041-22-9]

β-D-Glucan [9041-22-9]

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Référence orb1983179-50mg

Conditionnement : 50mg

Marque : Biorbyt


β-D-Glucan

SKU: orb1983179

Description

This research-grade β-D-Glucan is a bioactive small molecule known for its antitumor activity via targeting tumor-associated macrophages. It also modulates immune responses, showing relevance in models of necrotizing pancreatitis. Its applications span immunology and oncology research in both in vitro and in vivo experimental settings.

Research Area

Immunology & Inflammation

Images & Validation

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β-D-Glucan

Key Properties

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CAS Number9041-22-9
MW504.438
FormulaC18H32O16
SMILES05[C@]1(CO)O[C@](05)(O)[C@](05)(O)[C@@](05)(O)C1O[C@]1(05)O[C@](05)(CO)C(O[C@]2(05)O[C@](05)(CO)[C@@](05)(O)[C@](05)(O)[C@@]2(05)O)[C@](05)(O)[C@@]1(05)O
TargetOthers
SolubilityNaOH:10 mg/mL

Bioactivity

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In Vitro
Dissolving β-D-glucan in DMSO, but not in water, results in a concentration-dependent inhibition of MCF-7 cell proliferation, as determined by BrdU incorporation, with an IC50 of approximately 164 μg/mL. β-D-glucan, when dissolved in DMSO, inhibits the proliferation of tamoxifen/endocrine-resistant LCC9 and LY2 cells with IC50 values of 4.6 and 24.2 μg/mL, respectively.

Storage & Handling

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Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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