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> 6'-Sialyllactose [35890-39-2]

6'-Sialyllactose [35890-39-2]

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Référence HY-N10521-1mL

Conditionnement : 10mM/1mL

Marque : MedChemExpress


Description

6'-Sialyllactose promotes the growth of beneficial bacteria (such as Bifidobacterium and lactobacillus) and inhibits the proliferation of harmful bacteria. 6'-Sialyllactose exhibits anti-inflammatory and anti-angiogenic activities. 6'-Sialyllactose promotes the muscle health[1][2][3][4].

In Vitro

6'-Sialyllactose (0-50 μM, 24 h) inhibits Dihydrotestosterone-induced proliferation of HUVECs, suppresses tubular structure formation, inhibits the activation of VEGFR-2-related Akt-ERK signaling pathway[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

6'-Sialyllactose Related Antibodies

Western Blot Analysis[4]

Cell Line: HUVEC
Concentration: 0-50 μM
Incubation Time: 24 h
Result: Downregulated levels of p-Akt and p-ERK.
In Vivo

6'-Sialyllactose (5% added to mouse diet, 2 weeks) alleviates the anxiety-like behavior of mice, regulates the flora composition in social disruption (SDR)-stressed mouse model[2].
6'-Sialyllactose (100 mg/kg, po, once daily, 5 times a week for 12 weeks) increases the muscle mass and strength, thereby improving the exercise endurance of mice[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: SDR-stressed mouse model[2]
Dosage: 5% added to mouse diet
Administration: po, 2 weeks
Result: Reduced the anxiety-like behavior in open field tests.
Maintained the number of DCX-positive cells in the hippocampus.
Animal Model: C57BL/6J mouse models[3]
Dosage: 100 mg/kg
Administration: po, once daily, 5 times a week for 12 weeks
Result: Increased the mouse running distance.
Increased the absolute weight of gastrocnemius and soleus muscles.
Masse moléculaire

633.55

Formule

C23H39NO19
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@@H]([C@@H]([C@H]([C@H]1O)O)O)O[C@@H]1CO[C@]2(O[C@@]([C@@H]([C@H](C2)O)NC(C)=O)(18)[C@H](O)[C@H](O)CO)C(O)=O
Structure Classification
Initial Source

Clostridium perfringens
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvant et solubilité
In Vitro: 

H2O : ≥ 50 mg/mL (78.92 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5784 mL 7.8920 mL 15.7841 mL
5 mM 0.3157 mL 1.5784 mL 3.1568 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Calculateur de molarité

  • Calculateur de dilution

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Pureté et documentation
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