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Abscisic Acid [21293-29-8]

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Référence NB-64-34250-100mg

Conditionnement : 100mg

Marque : Neo Biotech

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Abscisic Acid

(Synonyms: Dormin, Abscisin II, Abscisic Acid (Dormin), (+)-ABA) Copy Product Info

Synonyms: Dormin, Abscisin II, Abscisic Acid (Dormin), (+)-ABA

Catalog No. T6368 Copy Product Info

Purity: 99.73%

Abscisic Acid (Dormin) is a plant hormone, which is involved in many plant developmental processes, modulates ion homeostasis and metabolism, and inhibits germination and seedling growth.

Cas No. 21293-29-8

For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:99.73%

Appearance:Solid

Color:White

Product Introduction

Abscisic Acid AI Summary

Abscisic Acid exhibits significant bioactivity across various assays, demonstrating its potential as an inhibitor of multiple biological processes. It shows potent inhibitory effects on seed germination and seedling elongation in species such as Arabidopsis thaliana, Lactuca sativa, Spinacia oleracea, and Oryza sativa, with IC50 values in the low nanomolar range for some species. Specifically, it inhibits barley seeds' alpha-amylase induction with an IC50 of 501.19 nM and cress seed germination at 977.24 nM. Additionally, it affects lettuce seed germination and rice seedling elongation with IC50 values of 12000.0 nM and 2000.0 nM, respectively. In biochemical contexts, Abscisic Acid inhibits ABI1 and ABI2 with IC50 values of 60.0 nM and 70.0 nM, respectively, and increases intracellular cAMP levels in human granulocytes, showing 35.0% activity at 1 uM. It also demonstrates antineuroinflammatory properties, inhibiting LPS-induced nitric oxide production in mouse N9 cells with an IC50 of 68020.0 nM..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Abscisic Acid (Dormin) is a plant hormone, which is involved in many plant developmental processes, modulates ion homeostasis and metabolism, and inhibits germination and seedling growth.
Synonyms	Dormin, Abscisin II, Abscisic Acid (Dormin), (+)-ABA

Chemical Properties

Molecular Weight	264.32
Formula	C₁₅H₂₀O₄
Cas No.	21293-29-8
Smiles	C\C(\C=C\[C@@]1(O)C(C)=CC(=O)CC1(C)C)=C\C(O)=O
Relative Density.	1.193 g/cm3

Storage & Solubility Information

Storage

Store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 252 mg/mL (953.39 mM), Sonication is recommended.

Ethanol: 49 mg/mL (185.38 mM), Sonication is recommended.

H2O: < 1 mg/mL (insoluble or slightly soluble)

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 5 mg/mL (18.92 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	3.7833 mL	18.9165 mL	37.8329 mL	189.1646 mL
5 mM	0.7567 mL	3.7833 mL	7.5666 mL	37.8329 mL
10 mM	0.3783 mL	1.8916 mL	3.7833 mL	18.9165 mL
20 mM	0.1892 mL	0.9458 mL	1.8916 mL	9.4582 mL
50 mM	0.0757 mL	0.3783 mL	0.7567 mL	3.7833 mL
100 mM	0.0378 mL	0.1892 mL	0.3783 mL	1.8916 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

Keywords

ProtonpumpProton pumporallyLANCL2insulin-sensitizingInhibitorinhibitH+-ATPaseEndogenousMetaboliteEndogenous MetabolitediabetesCa2+Abscisic AcidABA

Related Tags: Abscisic Acid chemical structure | Abscisic Acid formula | Abscisic Acid molecular weight