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> ELAVL2, ID (ELAVL2, HUB, ELAV-like protein 2, ELAV-like neuronal protein 1, Hu-antigen B, Nervous system-specific RNA-binding protein Hel-N1)

ELAVL2, ID (ELAVL2, HUB, ELAV-like protein 2, ELAV-like neuronal protein 1, Hu-antigen B, Nervous system-specific RNA-binding protein Hel-N1)

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Référence 035027-200ul

Conditionnement : 200ul

Marque : US Biological


035027 ELAVL2, ID (ELAVL2, HUB, ELAV-like protein 2, ELAV-like neuronal protein 1, Hu-antigen B, Nervous system-specific RNA-binding protein Hel-N1)

Clone Type
Polyclonal
Host
rabbit
Source
human
Swiss Prot
Q12926
Isotype
IgG
Grade
Affinity Purified
Applications
E FC IHC WB
Crossreactivity
Hu Mo
Accession #
NP_001164666.1; NP_001164668.1
Gene #
ELAVL2
Shipping Temp
Blue Ice
Storage Temp
-20°C

The protein encoded by this gene is a neural-specific RNA-binding protein that is known to bind to several 3' UTRs, including its own and also that of FOS and ID. The encoded protein may recognize a GAAA motif in the RNA. Three transcript variants encoding two different isoforms have been found for this gene.

Applications:
Suitable for use in Western Blot, Immunohistochemistry, Indirect Flow Cytometry and ELISA. Other applications not tested.

Recommended Dilutions:
Western Blot: 1:1000
Immunohistochemistry (FFPE): 1:100. Requires HIER using EDTA, pH 9.0 prior to staining.
Indirect Flow Cytometry (Indirect): 1:10-1:50
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Applications
Product Type: Pab|Isotype: IgG|Host: rabbit|Source: human|Concentration: Not Determined |Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide|Purity: Purified by Protein A and peptide affinity chromatography|Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 155-184 from the Central region of human ELAVL2. Species Sequence Homology: rat and Xenopus|Specificity: Recognizes human ELAVL2. Species Crossreactivity: mouse||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 155-184 from the Central region of human ELAVL2. Species Sequence Homology: rat and Xenopus
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide
Purity
Purified by Protein A and peptide affinity chromatography
Specificity
Recognizes human ELAVL2. Species Crossreactivity: mouse
References
1. Marroni, F., et al. Circ Cardiovasc Genet 2(4):322-328(2009). 2. Lowe, J.K., et al. PLoS Genet. 5 (2), E1000365 (2009). 3. D'Alessandro, V., et al. Cell. Oncol. 30(4):291-297(2008). 4. Jonson, L., et al. Mol. Cell Proteomics 6(5):798-811(2007). 5. Yano, M., et al. J. Biol. Chem. 280(13):12690-12699(2005)