fumarate hydratase (J-13)
Référence sc-100743
Conditionnement : 100µg/ml
Marque : Santa Cruz Biotechnology
Contactez votre distributeur local :
Téléphone : +1 850 650 7790
Click on image or enlarge button to enlarge
Anticorps fumarate hydratase (J-13): sc-100743
- L'Anticorps fumarate hydratase (J-13) est un monoclonal de souris IgG2b κ, cité dans 59 publications, fourni en 100 µg/ml
- dirigé contre la fumarate hydratase recombinante d'origine human
- recommandé pour la détection de precursor mitochondrial and cytoplasmic mature chains of fumarate hydratase d'origine human par WB, IP, IF, IHC(P) et ELISA
- 2b BP-HRP">m-IgG2b BP-HRP et m-IgGκ BP-HRP sont les réactifs secondaires recommandés pour la détection de l'anticorps fumarate hydratase (J-13) pour des applications de WB and IHC(P). Ces réactifs sont maintenant proposés en kit avec l'anticorps fumarate hydratase (J-13) ().
ACCÈS RAPIDE AUX LIENS
and Cruz Marker™ MW Standards Promotional
fumarate hydratase Antibody (J-13) is an IgG2b κ mouse monoclonal fumarate hydratase antibody that detects precursor mitochondrial and cytoplasmic mature chains of fumarate hydratase of human origin by WB, IP, IF, IHC(P) and ELISA. fumarate hydratase Antibody (J-13) is available as the non-conjugated anti-fumarate hydratase antibody form. Fumarate hydratase, a ubiquitously expressed mitochondrial enzyme, catalyses the reversible hydration of fumaric acid to yield l-malic acid during the Krebs cycle. Germline mutations in the fumarate hydratase gene cause a predisposition to renal defects such as multiple cutaneous and uterine leiomyoma (MCL) syndrome. Furthermore, mutations also correlate with renal and smooth muscle tumors, but not with prostate cancer. Additionally, like other metabolic diseases, fumarate hydratase deficiency correlates with seizures, due to prenatal brain dysgenesis.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
References:
- Defects of pyruvate metabolism and the Krebs cycle. | De Meirleir, L. 2002. J Child Neurol. 17 Suppl 3: 3S26-33; discussion 3S33-4. PMID: 12597053
- A role for mitochondrial enzymes in inherited neoplasia and beyond. | Eng, C., et al. 2003. Nat Rev Cancer. 3: 193-202. PMID: 12612654
- Germline mutations in fumarate hydratase (FH) do not predispose to prostate cancer. | Bevan, S., et al. 2003. Prostate Cancer Prostatic Dis. 6: 12-4. PMID: 12664059
- Germline fumarate hydratase mutations in families with multiple cutaneous and uterine leiomyomata. | Martinez-Mir, A., et al. 2003. J Invest Dermatol. 121: 741-4. PMID: 14632190
| Espèces | Nom du Gène | Gene ID | Localisation chromosomique | Numéro d'accession de l'isoforme (ARNm) | Numéro d'accès aux protéines | Numéro OMIM™ |
|---|---|---|---|---|---|---|
| Human | FH | Entrez Gene ID: 2271 | 1q43 | XM_011544132, NM_000143 | UniProt ID: P07954 | 606812 |
Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz® conjugates which eliminates the need for a secondary antibody.
Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-fumarate hydratase Antibody (J-13) has 59 citations in a variety of scientific publications.
Primary antibodies like Anti-fumarate hydratase Antibody (J-13) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.
L'anticorps fumarate hydratase préféré est l'Anticorps fumarate hydratase (H-6): sc-393992.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps fumarate hydratase (J-13) | sc-100743 | 100 µg/ml | .00 | |||
fumarate hydratase (J-13): m-IgGκ BP-HRP Kit | sc-534516 | 100 µg Ab; 40 µg BP | .00 | |||
fumarate hydratase (J-13): m-IgG2b BP-HRP Kit | sc-549264 | 100 µg Ab; 10 µg BP | .00 |
I am studying fumarate hydratase, but not in human samples. Will this antibody work in other species?
- y_2024, m_5, d_27, h_4CST
- bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
- cp_1, bvpage1
- co_hasquestionsanswers, tq_1
- loc_fr_FR, sid_100743, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
- clientName_scbt
- bvseo_sdk, java_sdk, bvseo-4.0.0
- CLOUD, getContent, 107ms
- QUESTIONS, PRODUCT
- y_2024, m_5, d_27, h_4
- bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
- cp_1, bvpage1
- co_hasreviews, tv_0, tr_5
- loc_fr_FR, sid_100743, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
- clientName_scbt
- bvseo_sdk, java_sdk, bvseo-4.0.0
- CLOUD, getReviews, 7ms
- REVIEWS, PRODUCT
- y_2024, m_5, d_27, h_4
- bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
- cp_1, bvpage1
- co_hasreviews, tv_0, tr_5
- loc_fr_FR, sid_100743, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
- clientName_scbt
- bvseo_sdk, java_sdk, bvseo-4.0.0
- CLOUD, getAggregateRating, 83ms
- REVIEWS, PRODUCT