Human Muscle Skeletal Receptor Tyrosine Kinase Antibody, MUSK Ab ELISA Kit
Référence MBS705762-96
Conditionnement : 96-Strip-Wells
Marque : MyBiosource
Muscle Skeletal Receptor Tyrosine Kinase Antibody (MUSK Ab) (MUSK) ELISA Kit for Human
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS705762Principle of the Assay: This assay employs the qualitative enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with antigen. Samples are pipetted into the wells with anti-human immunoglobulin conjugated Horseradish… More details
Product Overview
Online Datasheet in PDFProduct Name
Muscle Skeletal Receptor Tyrosine Kinase Antibody (MUSK Ab), ELISA Kit
Full Product Name
Human Muscle Skeletal Receptor Tyrosine Kinase Antibody, MUSK Ab ELISA Kit
Product Gene Name
MUSK elisa kit
Product Synonym Names
Human Muscle Skeletal Receptor Tyrosine Kinase Antibody (MUSK Ab) ELISA Kit; Muscle Skeletal Receptor Tyrosine Kinase Antibody (MUSK Ab)
Species Reactivity
Human
Samples
Serum
Specificity
This assay has high sensitivity and excellent specificity for detection of human MUSK antibody. No significant cross-reactivity or interference between human MUSK antibody and analogues was observed.
Preparation and Storage
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
Inter-assay Precision
Inter-assay Precision (Precision between assays): CV%<15%. Three samples of known concentration were tested in twenty assays to assess.
Intra-assay Precision
Intra-assay Precision (Precision within an assay): CV%<15%. Three samples of known concentration were tested twenty times on one plate to assess.
Molecular Weight
105,589 Da
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of MUSK elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for MUSK purchase
MBS705762 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Muscle Skeletal Receptor Tyrosine Kinase Antibody (MUSK Ab) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing MUSK. The ELISA analytical biochemical technique of the MBS705762 kit is based on MUSK antibody-MUSK antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect MUSK antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, MUSK. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Additional Details
NCBI/Uniprot data below describe general gene information for MUSK. It may not necessarily be applicable to this product.
NCBI Official Full Name
muscle, skeletal receptor tyrosine protein kinase
NCBI Official Synonym Full Names
muscle, skeletal, receptor tyrosine kinase
NCBI Official Symbol
MUSK
UniProt Protein Name
Muscle, skeletal receptor tyrosine protein kinase
UniProt Synonym Protein Names
Muscle-specific tyrosine protein kinase receptor; MuSK; Muscle-specific kinase receptor
Protein Family
Muscle, skeletal receptor tyrosine protein kinase
UniProt Gene Name
MUSK
UniProt Synonym Gene Names
MuSK; Muscle-specific kinase receptor
UniProt Entry Name
MUSK_CHICK
NCBI Protein Information
muscle, skeletal receptor tyrosine protein kinase; muscle-specific kinase receptor; muscle-specific tyrosine protein kinase receptor
UniProt Comments for MUSK
Function: Receptor tyrosine kinase which plays a central role in the formation and the maintenance of the neuromuscular junction (NMJ), the synapse between the motor neuron and the skeletal muscle. Recruitment of AGRIN by LRP4 to the MUSK signaling complex induces phosphorylation and activation of MUSK, the kinase of the complex. The activation of MUSK in myotubes regulates the formation of NMJs through the regulation of different processes including the specific expression of genes in subsynaptic nuclei, the reorganization of the actin cytoskeleton and the clustering of the acetylcholine receptors (AChR) in the postsynaptic membrane. May also play a role within the central nervous system by mediating cholinergic responses, synaptic plasticity and memory formation 1 PublicationManual assertion based on experiment in:Ref.1
Catalytic activity: ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
Show more Catalytic activity: ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with MUSK elisa kit
| Reference Product | PubMed Publications |
|---|---|
| DOK7 elisa kit | >31 publications with MUSK and DOK7 |
| AGRN elisa kit | >7 publications with MUSK and AGRN |
| PTPN11 elisa kit | >5 publications with MUSK and PTPN11 |
| RAPSN elisa kit | >5 publications with MUSK and RAPSN |
| CHRNA3 elisa kit | >1 publications with MUSK and CHRNA3 |
Diseases associated with MUSK elisa kit
| Disease Name | Pubmed Publications |
|---|---|
| Nervous System Diseases Antibodies | >386 publications with MUSK and Nervous System Diseases |
| Myasthenia Gravis Antibodies | >358 publications with MUSK and Myasthenia Gravis |
| Disease Models, Animal Antibodies | >97 publications with MUSK and Disease Models, Animal |
| Atrophy Antibodies | >49 publications with MUSK and Atrophy |
| Fibrosis Antibodies | >36 publications with MUSK and Fibrosis |
| Inflammation Antibodies | >34 publications with MUSK and Inflammation |
| Necrosis Antibodies | >21 publications with MUSK and Necrosis |
| Poisoning Antibodies | >20 publications with MUSK and Poisoning |
| Fatty Liver Antibodies | >20 publications with MUSK and Fatty Liver |
| Liver Diseases Antibodies | >18 publications with MUSK and Liver Diseases |
Organs/Tissues associated with MUSK elisa kit
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Muscle Antibodies | >488 publications with MUSK and Muscle |
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