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> Inulin [9005-80-5]

Inulin [9005-80-5]

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Référence orb1300674-25g

Conditionnement : 25g

Marque : Biorbyt


Inulin

SKU: orb1300674

Description

Inulin, a fructosan starch derived from plant tubers and roots, is hydrolyzable to fructose. It is widely used in research as a prebiotic to study gut microbiota, in renal function diagnostics, and as a carrier in pharmaceutical formulations for both in vitro and in vivo studies.

Research Area

Metabolism Research

Images & Validation

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Inulin

Key Properties

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CAS Number9005-80-5
MW490.411
Purity≥95% (May vary between batches)
FormulaC17H30O16
SMILESOC[C@H]1O[C@@](CO)(OC[C@@]2(O[C@H]3O[C@H](O)[C@@H](O)[C@H](O)[C@H]3O)O[C@H](CO)[C@@H](O)[C@@H]2O)[C@@H](O)[C@@H]1O
TargetEndogenous Metabolite,Others
SolubilityEthanol:< 1 mg/mL (insoluble or slightly soluble);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL;H2O:95 mg/mL;DMSO:105 mg/mL

Bioactivity

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In Vivo
Inulin results in an increase in caecal wt and beta-glucosidase activity and a decrease in caecal pH were observed in rats given inulin-containing diets (with or without B. longum).
In Vitro
Inulin causes (20 g/d and 40 g/d) a significant increase in bifidobacterial counts in feces. Inulin exerts a preferential stimulatory effect on numbers of the health-promoting genus Bifidobacterium, whilst maintaining populations of potential pathogens (Escherichia coli, Clostridium) at relatively low levels. Inulin combined with Bifidobacterium results in more potent inhibition of aberrant crypt foci (ACF) than administration of the two separately, achieving 80% inhibition of small ACF. Inulin is made by a set of linear chains of fructose molecules, with a degree of polymerization (DP) ranging between 3 and 65, it can be fractionated into a slowly fermentable long-chain fraction (DP ranging from 10 to 65, average 25) or in a rapidly fermentable fraction made of oligofructose (DP ranging from 3 to 8, average 4). Long-chain inulin combined with short-chain oligofructose results in larger numbers of caecal, colonic and faecal bacteria of the Clostridium coccoides-Eubacterium rectale cluster than Control in rats, whereas OF alone does not affect this bacterial group in caecum, colon or faeces.

Storage & Handling

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Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

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Inhibitor, inhibit, Inulin
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    1. Fructan Colorimetric Microplate Assay Kit

    Fructan Colorimetric Microplate Assay Kit [orb3073222]

    All

    0.05 mg/ml - 5 mg/ml

    100 assay
  • FITC-inulin

    FITC-inulin [orb2944573]

    10 mg, 50 mg
  • Fructo-oligosaccharide DP13

    Fructo-oligosaccharide DP13 [orb1942396]

    137405-37-9

    2125.84

    C78H132O66

    5 mg, 50 mg
  • Inulin

    Inulin [orb1221671]

    >98% (HPLC)

    9005-80-5

    ——

    C6nH10n+2O5n+1

    100 mg, 200 mg, 500 mg, 1 g

Compound Identifiers

PubChem CID
129520965 ↗

Key Properties

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Protocol Information