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> Kdo2-Lipid A ammonium [1246298-62-3]

Kdo2-Lipid A ammonium [1246298-62-3]

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Référence T38635-1mg

Conditionnement : 1mg

Marque : TargetMol


Kdo2-Lipid A ammonium

Kdo2-Lipid A ammonium

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Kdo2-Lipid A ammonium
Cas No. 1246298-62-3
Other Forms of Kdo2-Lipid A ammonium:
Kdo2-Lipid ATYD-00998123621-04-5
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For research use only—not for human use. No sales to individuals. Use as intended only.

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Appearance:Solid
Color:White

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Product Introduction

Bioactivity
Description
Kdo2-Lipid A ammonium (KLA) is a selective and potent TLR4 agonist, a lipopolysaccharide.Kdo2-Lipid A ammonium induces the release of TNF and PGE2.
In vitro
Stimulation with Kdo2-Lipid A ammonium (1 µM) induces the release of both TNF and PGE2 from the cell cultures of adult rat spinal astrocytes[1].
In vivo
Upon intrathecal administration, KDO2-Lipid A ammonium activates toll-like receptor 4 (TLR4) in rats[1].
Chemical Properties
Molecular Weight2306.84
FormulaC110H214N6O39P2
Cas No.1246298-62-3
SmilesCCCCCCCCCCCCCC(O[C@H](CCCCCCCCCCC)CC(O[C@@H]1[C@H]([C@@H](O[C@@H]([C@H]1OP([O-])([O-])=O)CO[C@@]2(C[C@H]([C@@H]([C@@](O2)(15)[C@H](O)CO)O)O[C@]3(O[C@]([C@H]([C@@H](C3)O)O)(15)[C@H](O)CO)C(O)=O)C(O)=O)OC[C@@H]4[C@H]([C@@H]([C@H]([C@H](O4)OP([O-])([O-])=O)NC(C[C@H](O)CCCCCCCCCCC)=O)OC(C[C@H](O)CCCCCCCCCCC)=O)O)NC(C[C@@H](CCCCCCCCCCC)OC(CCCCCCCCCCC)=O)=O)=O)=O.[NH4+].[NH4+].[NH4+].[NH4+]
Storage & Solubility Information
StorageShipping with blue ice/Shipping at ambient temperature.