10210 | RHODAMINE 110 D2R 2mg Clinisciences

D2R

D₂R (Rhodamine 110, bis-(L-aspartic acid amide), ditrifluoroacetic acid salt) is a general substrate for caspases including caspases 3 and 7. Unlike other fluorogenic substrates for caspases, D₂R appears to be membrane-permeant, and thus can be used to measure caspase activity in live cells without osmotic shock for flow cytometry studies, as well as for cell extracts.

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Product Description

D₂R (Rhodamine 110, bis-(L-aspartic acid amide), ditrifluoroacetic acid salt) is a general substrate for caspases including caspases 3 and 7. Unlike other fluorogenic substrates for caspases, D₂R appears to be membrane-permeant, and thus can be used to measure caspase activity in live cells without osmotic shock for flow cytometry studies, as well as for cell extracts. For real-time detection of caspase-3 activity in intact cells, see our novel NucView®488 Caspase-3 Substrate.

Ex/Em of end product (R110) = 496/520 nm
Off-white to pink solid soluble in DMSO
Store at 4°C and protect from light
C₃₂H₂₆F₆N₄O₁₃
MW: 788.57

Technology

Cell Viability & Apoptosis

Cellular Stains

Product Attributes

Size

2 mg

Excitation/Emission

496/520 nm (end product)

Documents, Protocols, SDS and COA

Protocols

PI-10210

SDS

SDS-10210

COA

Request the Certificate of Analysis

References

1. Biochemistry 38, 13906 (1999).

Citations