TIMP2, Recombinant, Human, aa27-220, His-Tag (Metalloproteinase inhibitor 2, CSC-21K, DDC8)

TIMP2, also known as metalloproteinase inhibitor 2, belongs to the tissue inhibitors of metalloproteinases family. The TIMP family inhibit most MMPs by forming non-covalent binary complex. TIMP2 plays a unique role among TIMP family members owing to its functions to regulate cellular responses to growth factors.

Recombinant protein corresponding to aa27-220 from human TIMP2, fused to His-tag at C-terminal expressed in Insect cell.

~22.5kD (200aa)

CSCSPVHPQQ AFCNADVVIR AKAVSEKEVD SGNDIYGNPI KRIQYEIKQI KMFKGPEKDI EFIYTAPSSA VCGVSLDVGG KKEYLIAGKA EGDGKMHITL CDFIVPWDTL STTQKKSLNH RYQMGCECKI TRCPMIPCYI SSPDECLWMD WVTEKNINGH QAKFFACIKR SDGSCAWYRG AAPPKQEFLD IEDPHHHHHH

Endotoxin: ~1EU/1ug (LAL)

May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Recombinant, insect cell line

≥95% (SDS-PAGE)

~0.1mg/ml

Supplied as a liquid in PBS, pH 7.4, 10% glycerol.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.