Reagentes e instrumentos para imunologia, biologia celular e biologia molecular.

Anti-DKK1 Antibody (7O196)

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Tamanho : 100uL

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(Synonyms: dickkopf WNT signaling pathway inhibitor 1) Copy Product Info

Synonyms: dickkopf WNT signaling pathway inhibitor 1

Catalog No. TMAY-00397 Copy Product Info

Anti-DKK1 Antibody (7O196) is a Rabbit antibody targeting DKK1. Anti-DKK1 Antibody (7O196) can be used in ELISA.

For research use only—not for human use. No sales to individuals. Use as intended only.

Product Information

Bioactivity

Description	Anti-DKK1 Antibody (7O196) is a Rabbit antibody targeting DKK1. Anti-DKK1 Antibody (7O196) can be used in ELISA.
Synonyms	dickkopf WNT signaling pathway inhibitor 1
Ig Type	Rabbit IgG
Clone	7O196
Reactivity	Human
Specificity	Human DKK-1
Application	ELISA
Recommended Dose	ELISA: 1:5000-1:10000
Antibody Type	Monoclonal
Host Species	Rabbit
Construction	This antibody was obtained from a rabbit immunized with purified, recombinant Human dickkopf related protein 1 (rh Dkk1; TMPY-00775; Met 2-His 266; NP_036374.1).
Purification	Protein A
Appearance	Liquid
Formulation	0.2 μm filtered solution in PBS
Research Background	Dickkopf (DKK) family proteins, consisting of DKK-1, DKK-2, DKK-3 and DKK-4, function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5/6. DKK-1, DKK-2, and DKK-4 also bind cell surface Kremen-1 or Kremen-2 and promote the internalization of LRP5/6. Dickkopf related protein 1 (DKK-1) was initially identified as an inducer of head formation in Xenopus embryos. DKK-1 protein modulates Wnt signaling pathway during embryonic development. Increased levels of DKK-1 are found in the majority of lung cancers, esophageal squamous cell carcinomas, and hormone-resistant breast cancers, while DKK-1 expression is decreased in malignant melanoma and colorectal cancers.

Related Conjugates and Formulations

Conjucates	Unconjugated

Antigen Details

Immunogen	Recombinant Protein: Human Dkk1 protein (TMPY-00775)
Antigen Species	Human

Stability & Storage

Stability & Storage	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
Transport	Shipping with blue ice.

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