Antiviral agent 45

Antiviral agent 45 (compound 9a) is an antiviral agent. Antiviral agent 45 inhibits HIV-1 andHIV-2 with IC₅₀s of 35 and 3.1 nM, respectively^[1].

901.23

C₄₇H₉₄N₆O₆P₂

NC1=NC=NC2=C1N=CN2C[C@@H](C)OCP(OP(OCCCC)(CCCCCCCCCCCCCCCCCC)=O)([O-])=O.CCCC[N+](CCCC)(CCCC)CCCC

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Jia X, et al. Membrane-permeable tenofovir-di- and monophosphate analogues. Eur J Med Chem. 2023 Dec 11;264:116020.  [Content Brief]