Antiviral agent 73

Antiviralagent 73 (compound D13) is a potent inhibitor of intercellular movement with antiviral activity. It inactivates the Potato virus Y (PVY) with an EC50 value of 79.5 μg/mL. By forming stable hydrogen bonds with the Pro154 of the PVY coat protein, Antiviralagent 73 effectively hinders viral infection. Additionally, it disrupts Pro154-mediated intercellular viral transport through plasmodesmata. Antiviralagent 73 is applicable for the prevention and control of plant viruses.