CD14 antibody [MEM-15] (PE-Cy5)
Referência GTX20760-09-100test
Tamanho : 100test
Marca : Genetex
Contactar o distribuidor local :
Telefone : +1 850 650 7790
Host | Mouse |
|---|---|
Clonality | Monoclonal |
Clone Name | MEM-15 |
Isotype | IgG1 |
Application | FACS |
Reactivity | Human, Primate |
| Package | 100 test |
Datasheet File View product citations for antibody GTX20760-09 on CiteAb
APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application | Recommended Dilution |
|---|---|
| FACS | 4 μl reagent / 100 μl of whole blood or 10⁶ cells in a suspension |
Not tested in other applications.
Calculated MW
40 kDa. ( Note )
Product Note
This antibody reacts with CD14, a 53-55 kDa GPI (glycosylphosphatidylinositol)-linked membrane glycoprotein expressed on monocytes, macrophages and weakly on granulocytes; also expressed by most tissue macrophages. And this antibody also reacts with soluble forms of CD14 found in serum and in the urine of some nephrotic patients.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
15mM Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
A crude mixture of human urinary proteins precipitated by ammonium sulphate from the urine of a patient suffering from proteinuria.
Purification
Purified by size-exclusion chromatography
Conjugation
Phycoerythrin-Cyanine5 (PE-Cy5)
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. Cy and CyDye are trademarks of GE Healthcare.
TARGET
Synonyms
CD14 , CD14 molecule
Cellular Localization
Cell membrane
Background
The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Mar 2010]
Database
Clone Reference
Popescu NI et al. Microorganisms 2022; 10 (3) Internalization of Polymeric Bacterial Peptidoglycan Occurs through Either Actin or Dynamin Dependent Pathways.
REVIEW
Clone Reference
Popescu NI et al. Microorganisms 2022; 10 (3) Internalization of Polymeric Bacterial Peptidoglycan Occurs through Either Actin or Dynamin Dependent Pathways.
| SDS | |
|---|---|
| PBS.pdf | |
| Sodium Azide.pdf | |