CD86 antibody [BU63] (PE-Cy5)
Referência GTX00600-09-100test
Tamanho : 100test
Marca : Genetex
Host | Mouse |
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Clonality | Monoclonal |
Clone Name | BU63 |
Isotype | IgG1 |
Application | FACS |
Reactivity | Human |
Package | 100 test |
View product citations for antibody GTX00600-09 on CiteAb
APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application | Recommended Dilution |
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FACS | 4 μl reagent / 100 μl of whole blood or 10⁶ cells in a suspension |
Not tested in other applications.
Calculated MW
38 kDa. ( Note )
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
15mM Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
B-lymphoblastoid cell line ARH 77
Purification
Purified by size-exclusion chromatography
Conjugation
Phycoerythrin-Cyanine5 (PE-Cy5)
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. Cy and CyDye are trademarks of GE Healthcare.
TARGET
Synonyms
B7.2 , B70 , B72 , CD28LG2 , CD86 , CD86 molecule , LAB72 , B7-2
Cellular Localization
Cell membrane
Background
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011]
Database
Clone Reference
Manferdini C et al. Biology (Basel) 2020; 9 (12) Impact of Isolation Procedures on the Development of a Preclinical Synovial Fibroblasts/Macrophages in an In Vitro Model of Osteoarthritis.
Tsai PY et al. Int J Mol Sci 2019; 20 (23) NLRP7 Is Involved in the Differentiation of the Decidual Macrophages.
Carbone F et al. Int J Cardiol 2018; (Epub) Serum levels of osteopontin predict major adverse cardiovascular events in patients with severe carotid artery stenosis.
Wang LT et al. Cancer Res 2017; (Epub) Intestine-specific homeobox gene ISX integrates interleukin-6 signaling, tryptophan catabolism and immune suppression.
REVIEW
Clone Reference
Manferdini C et al. Biology (Basel) 2020; 9 (12) Impact of Isolation Procedures on the Development of a Preclinical Synovial Fibroblasts/Macrophages in an In Vitro Model of Osteoarthritis.
Tsai PY et al. Int J Mol Sci 2019; 20 (23) NLRP7 Is Involved in the Differentiation of the Decidual Macrophages.
Carbone F et al. Int J Cardiol 2018; (Epub) Serum levels of osteopontin predict major adverse cardiovascular events in patients with severe carotid artery stenosis.
Wang LT et al. Cancer Res 2017; (Epub) Intestine-specific homeobox gene ISX integrates interleukin-6 signaling, tryptophan catabolism and immune suppression.
SDS | |
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PBS.pdf | |
Sodium Azide.pdf |