CD9 (BA2, DRAP27, Leukocyte antigen MIC3, MIC3, Motility related protein, MRP1, P24, Tetraspanin 29, Tspan29) (AP)

Referência MBS6247783-5x0,1mL

Tamanho : 5x0.1mL

Marca : MyBiosource

CD9 (BA2, DRAP27, Leukocyte antigen MIC3, MIC3, Motility related protein, MRP1, P24, Tetraspanin 29, Tspan29) (AP)

CD9 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6247783

MBS6247783 is an antibody targeting CD9. Also known as CD9 (BA2, DRAP27, Leukocyte antigen MIC3, MIC3, Motility related protein, MRP1, P24, Tetraspanin 29, Tspan29) (AP). Reactive in Bovine, Canine, Equine, Feline, Human, Monkey, Porcine. Host: Mouse. More details

Product Overview

Online Datasheet in PDF
Product Name
CD9, Monoclonal Antibody
Full Product Name
CD9 (BA2, DRAP27, Leukocyte antigen MIC3, MIC3, Motility related protein, MRP1, P24, Tetraspanin 29, Tspan29) (AP)
Product Gene Name
anti-CD9 antibody
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
3H912
Host
Mouse
Species Reactivity
Bovine, Canine, Equine, Feline, Human, Monkey, Porcine
Form/Format
Supplied as a liquid in PBS, pH 7.2. Labeled with Alkaline Phosphatase.
Purity/Purification
Purified by Protein G Affinity Chromatography
Specificity
Recognizes CD9, a 24kD surface glycoprotein expressed by platelets, monocytes, some lymphocytes and endothelial cells. CD9 is a member of the tetraspan gene family. Species Crossreactivity: Clone is reported to crossreact with canine, feline, bovine, equine, lapine (2), Rhesus monkey and porcine
Preparation and Storage
Store at 4 degree C. Do Not Freeze.
Molecular Weight
25,416 Da
OMIM
143030
3D Structure
ModBase 3D Structure for P21926
Immunogen
Human platelet membrane.
Conjugate
AP

Product Categories/Family for anti-CD9 antibody

Antibodies; CD Markers

Product References and Citations for anti-CD9 antibody

1. Leucocyte Typing IV (1989) Ed Knapp W. et al. Oxford University Press.2. Brodersen, R. et al. (1998). Analysis of the immunological cross reactivities of 213 well characterized monoclonal antibodies with specificities agai

Other Notes

Small volumes of anti-CD9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CD9. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
MRP-1 (motility related protein)
NCBI Official Synonym Full Names
CD9 molecule
NCBI Official Symbol
CD9
NCBI Official Synonym Symbols
MIC3; MRP-1; BTCC-1; DRAP-27; TSPAN29; TSPAN-29
UniProt Protein Name
CD9 antigen
UniProt Synonym Protein Names
5H9 antigen; Cell growth-inhibiting gene 2 protein; Leukocyte antigen MIC3; Motility-related protein; MRP-1; Tetraspanin-29; Tspan-29; p24
Protein Family
CD9 antigen
UniProt Gene Name
CD9
UniProt Synonym Gene Names
MIC3; TSPAN29; MRP-1; Tspan-29
UniProt Entry Name
CD9_HUMAN
NCBI Protein Information
CD9 antigen; 5H9 antigen; tetraspanin-29; BA-2/p24 antigen; CD9 antigen (p24); leukocyte antigen MIC3; motility related protein-1; cell growth-inhibiting gene 2 protein

NCBI Summary for CD9

This gene encodes a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Tetraspanins are cell surface glycoproteins with four transmembrane domains that form multimeric complexes with other cell surface proteins. The encoded protein functions in many cellular processes including differentiation, adhesion, and signal transduction, and expression of this gene plays a critical role in the suppression of cancer cell motility and metastasis. [provided by RefSeq, Jan 2011]
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UniProt Comments for CD9

CD9: Involved in platelet activation and aggregation. Regulates paranodal junction formation. Involved in cell adhesion, cell motility and tumor metastasis. Required for sperm-egg fusion. Belongs to the tetraspanin (TM4SF) family.

Protein type: Motility/polarity/chemotaxis; Membrane protein, multi-pass; Cell adhesion; Membrane protein, integral

Chromosomal Location of Human Ortholog: 12p13.3

Cellular Component: extracellular space; platelet alpha granule membrane; focal adhesion; integral to plasma membrane; apical plasma membrane; plasma membrane; vesicle; external side of plasma membrane

Molecular Function: integrin binding; protein binding

Biological Process: negative regulation of cell proliferation; platelet activation; platelet degranulation; fusion of sperm to egg plasma membrane; single fertilization; pathogenesis; brain development; cell adhesion; cell motility; blood coagulation; oligodendrocyte development; response to water deprivation; multicellular organism reproduction; paranodal junction assembly
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CD9 antibody

 Reference Product  PubMed Publications
 CD36 antibody  >37 publications with CD9 and CD36
 IGSF8 antibody  >17 publications with CD9 and IGSF8
 PTGFRN antibody  >12 publications with CD9 and PTGFRN
 ITGA6 antibody  >3 publications with CD9 and ITGA6
 ERVWE1 antibody  >1 publications with CD9 and ERVWE1
 SCARB1 antibody  >1 publications with CD9 and SCARB1
 HBEGF antibody  >1 publications with CD9 and HBEGF

Pathways associated with anti-CD9 antibody

 Products by Pathway  Pathway Diagram
 Fertilization Pathway antibodies  Fertilization Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Platelet Activation, Signaling And Aggregation Pathway antibodies  Platelet Activation, Signaling And Aggregation Pathway Diagram
 Platelet Degranulation Pathway antibodies  Platelet Degranulation Pathway Diagram
 Reproduction Pathway antibodies  Reproduction Pathway Diagram
 Response To Elevated Platelet Cytosolic Ca2+ Pathway antibodies  Response To Elevated Platelet Cytosolic Ca2+ Pathway Diagram
 Sperm:Oocyte Membrane Binding Pathway antibodies  Sperm:Oocyte Membrane Binding Pathway Diagram
 A6b1 And A6b4 Integrin Signaling Pathway antibodies  A6b1 And A6b4 Integrin Signaling Pathway Diagram

Diseases associated with anti-CD9 antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >407 publications with CD9 and Neoplasms
 Carcinoma Antibodies  >127 publications with CD9 and Carcinoma
 Neoplasms, Germ Cell and Embryonal Antibodies  >57 publications with CD9 and Neoplasms, Germ Cell and Embryonal
 Leukemia, Myeloid, Acute Antibodies  >48 publications with CD9 and Leukemia, Myeloid, Acute
 Inflammation Antibodies  >43 publications with CD9 and Inflammation
 Cardiovascular Diseases Antibodies  >41 publications with CD9 and Cardiovascular Diseases
 Neoplasms, Experimental Antibodies  >36 publications with CD9 and Neoplasms, Experimental
 Lung Neoplasms Antibodies  >34 publications with CD9 and Lung Neoplasms
 Necrosis Antibodies  >31 publications with CD9 and Necrosis
 Breast Neoplasms Antibodies  >31 publications with CD9 and Breast Neoplasms

Organs/Tissues associated with anti-CD9 antibody

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >76 publications with CD9 and Lung
 Embryonic Tissue Antibodies  >62 publications with CD9 and Embryonic Tissue
 Uterus Antibodies  >33 publications with CD9 and Uterus
 Brain Antibodies  >31 publications with CD9 and Brain
 Prostate Antibodies  >23 publications with CD9 and Prostate
 Mixed Antibodies  >16 publications with CD9 and Mixed
 Mouth Antibodies  >12 publications with CD9 and Mouth
 Pharynx Antibodies  >10 publications with CD9 and Pharynx
 Intestine Antibodies  >10 publications with CD9 and Intestine
 Pancreas Antibodies  >8 publications with CD9 and Pancreas