Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human tonsil with CXCR4 polyclonal antibody (Cat # PAB26091).
Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
- Specifications
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CXCR4.
Immunogen
A synthetic peptide corresponding to 20 amino acids at cytoplasmic domain of human CXCR4.
Host
Rabbit
Reactivity
Chicken, Hamster, Human, Monkey, Mouse, Rabbit, Rat
Specificity
BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Form
Liquid
Purification
Immunoaffinity chromatography
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (9-14 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human tonsil with CXCR4 polyclonal antibody (Cat # PAB26091).
Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. - Gene Info — CXCR4
Entrez GeneID
7852Protein Accession#
P61073Gene Name
CXCR4
Gene Alias
CD184, D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM
Gene Description
chemokine (C-X-C motif) receptor 4
Gene Ontology
HyperlinkGene Summary
This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
Other Designations
C-X-C chemokine receptor type 4|CD184 antigen|chemokine (C-X-C motif), receptor 4 (fusin)|chemokine receptor 4|fusin|leukocyte-derived seven-transmembrane-domain receptor|lipopolysaccharide-associated protein 3|neuropeptide Y receptor Y3|seven transmembra
- Interactomes
- Pathways
- Diseases