store at low temperature,keep away from moisture,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Cyclo(L-Phe-L-Pro) [3705-26-8]
Referência TN6672-5mg
Tamanho : 5mg
Marca : TargetMol
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Cyclo(L-Phe-L-Pro)
Catalog No. TN6672 CAS 3705-26-8
Cyclo(L-Phe-L-Pro) shows broad-spectrum antibacterial and antifungal activities. Cyclo(L-Phe-L-Pro) exhibits activity against methicillin-resistant S. aureus and Enterococcus raffinosus.
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Cyclo(L-Phe-L-Pro), CAS 3705-26-8
| Description | Cyclo(L-Phe-L-Pro) shows broad-spectrum antibacterial and antifungal activities. Cyclo(L-Phe-L-Pro) exhibits activity against methicillin-resistant S. aureus and Enterococcus raffinosus. |
| In vitro | Cyclo(L-Phe-L-Pro) interferes with the activation of retinoic-acid-inducible gene-I and inhibits the production of IFN-β[2]. Cyclo(L-Phe-L-Pro) exhibits free-radical scavenging activity with an IC50 value of 24 µM for DPPH[3]. |
| Molecular Weight | 244.29 |
| Formula | C14H16N2O2 |
| CAS No. | 3705-26-8 |
Storage
Solubility Information
DMSO: 225.0 mg/mL (921.0 mM), Sonication is recommended.
References and Literature
1. Katrin Ström, et al. Lactobacillus plantarum MiLAB 393 Produces the Antifungal Cyclic Dipeptides Cyclo(L-Phe-L-Pro) and Cyclo(L-Phe-trans-4-OH-L-Pro) and 3-Phenyllactic Acid. Appl Environ Microbiol. 2002 Sep;68(9):4322-7. 2. Wooseong Lee, et al. Vibrio vulnificus quorum-sensing molecule cyclo(Phe-Pro) inhibits RIG-I-mediated antiviral innate immunity. Nat Commun. 2018 Apr 23;9(1):1606. 3. Keyong Ho Lee, et al. Radioprotective effect of cyclo(L-phenylalanyl-L-prolyl) on irradiated rat lung. J Microbiol Biotechnol. 2008 Feb;18(2):369-76.