D-(+)-Trehalose [99-20-7]
Referência NB-64-18876-50mg
Tamanho : 50mg
Marca : Neo Biotech
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D-(+)-Trehalose
(Synonyms: Trehalose, Mycose, Ergot Sugar, D-Trehalose, D-(+)-Trehalose Anhydrous) Copy Product InfoSynonyms: Trehalose, Mycose, Ergot Sugar, D-Trehalose, D-(+)-Trehalose Anhydrous
Catalog No. T2O2798 Copy Product Info
Purity: 99.82%
D-(+)-Trehalose (Mycose) can inhibit the decomposition of collagen, so it can be used to improve osteoporosis.
Cas No. 99-20-7
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.82%
Color:White
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Product Information
D-(+)-Trehalose AI Summary
D-(+)-Trehalose demonstrates a multifaceted bioactivity profile, including potential neuroprotective effects in R6/2 transgenic mice, where it significantly increased the mean survival time to 94.5 days at a 1% oral concentration, albeit with a 25.0% body weight loss after 12 weeks, indicating some toxicity concerns. The compound notably inhibits amyloid beta-40 and amyloid beta (1 to 42) aggregation across various structural forms (unordered, beta-turns, beta-sheets, alpha-helix) and concentrations, as well as reduces amyloid beta-40-induced cell death in C57BL/6 mouse primary cortical neurons. Additionally, D-(+)-Trehalose shows inhibitory activity against various T6PP enzymes from different organisms, with the highest activity against Brugia malayi T6PP. It exhibits antiviral properties against SARS-CoV-2 by inhibiting virus-induced cytotoxicity in Caco-2 and VERO-6 cells, with moderate inhibition of SARS-CoV-2 3CL-Pro protease at 20µM. The compound also demonstrates a binding affinity to Mycobacterium tuberculosis LpqY, with a dissociation constant (Kd) of 36100.0 nM, and shows weak inhibitory activity against human HDAC6. These diverse bioactivities suggest that D-(+)-Trehalose could be a promising candidate for further research and development in various therapeutic areas..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | D-(+)-Trehalose (Mycose) can inhibit the decomposition of collagen, so it can be used to improve osteoporosis. |
| Synonyms | Trehalose, Mycose, Ergot Sugar, D-Trehalose, D-(+)-Trehalose Anhydrous |
| Molecular Weight | 342.30 |
| Formula | C12H22O11 |
| Cas No. | 99-20-7 |
| Smiles | O([C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O |
| Relative Density. | 1.76 g/cm3 |
| Storage | Store under nitrogen, Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | H2O: 200 mg/mL (584.28 mM)  DMSO: 247.5 mg/mL (723.05 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
H2O/DMSO
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density. | ||||||||||||||||||||||||||||||||||||