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> Fullerene-C60 [99685-96-8]

Fullerene-C60 [99685-96-8]

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Referência orb1690098-500mg

Tamanho : 500mg

Marca : Biorbyt


Fullerene-C60

SKU: orb1690098

Description

Fullerene-C60

Research Area

Metabolism Research

Images & Validation

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Fullerene-C60

Key Properties

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CAS Number99685-96-8
MW720.64
FormulaC60
SMILESC=12C3=C4C=5C1C6=C7C=8C2=C9C%10=C3C=%11C%12=C4C%13=C%14C5C%15=C6C%16=C7C%17=C%18C8C9=C%19C%20=C%10C%11C%21=C%22C%12=C%13C%23=C%24C%14=C%15C%25=C%16C%26=C%17C=%27C%18=C%19C=%28C%20=C%21C=%29C%22=C%23C%30=C%24C%25=C%26C=%31C%27C%28C%29C%30%31
TargetFree radical scavengers
SolubilityH2O:< 1 mg/mL, insoluble;DMSO:< 1 mg/mL, insoluble

Bioactivity

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In Vitro
Methods: To estimate the accumulation of Fullerene-C60 in leukemic cells and to investigate its phototoxic effects on parental and cisplatin-treated leukemic cells. A stable homogeneous hydrocolloid solution of pristine C60 with an average nanoparticle diameter of 50 nm was used in the experiments. Fluorescently labeled C60 was synthesized by covalently coupling C60 with rhodamine B isothiocyanate. Results: Confocal microscopy Results showed that leukemic Jurkat cells could efficiently take up Fullerene-C60 from the culture medium. Light-emitting diode light (100 mW cm-2, λ = 420–700 nm) was used to excite the accumulated C60. When leukemic Jurkat cells were exposed to a combination of C60 and visible light treatment, a time-dependent decrease in viability was detected.

Storage & Handling

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Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

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Fullerene C60, FullereneC60, Fullerene-C60, Fullerene-C-60

Compound Identifiers

PubChem CID
123591 ↗

Key Properties

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No computed properties available.

Protocol Information