Tamanho : 10mg
Synonyms:
| Description | GSC-718 is a synthetic sialic acid glycan that acts as a ligand mimic for CD22. It is a potent inhibitor of CD22, with an IC50 value of 0.161 μM for mCD22. GSC-718 enhances B cell proliferation and boosts antibody production. It is applicable in studies related to B cell lymphoma and rheumatoid arthritis. |
| Molecular Weight | 648.64 |
| Formula | C32H37N2NaO11 |
| Cas No. | 2493080-16-1 |
| Smiles | O(CC1=CC=CC=C1)[C@@]2(C(O)=O)O[C@@]([C@@H]([C@@H](CNC(CC3=CC=C(C=C3)C4=CC=C(O)C=C4)=O)O)O)([C@H](NC(CO)=O)[C@@H](O)C2)19.[Na] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 µL Tween 80 and mix well until fully clarified.
3) Add 450 µL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
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