Havcr2 Rat Monoclonal Antibody [Clone ID: 25F.1D6]

Specifications

Product Data
Clone Name	25F.1D6
Applications	FC
Recommended Dilution	Immunohistochemistry. Flow Cytometry.
Reactivities	Mouse
Host	Rat
Isotype	IgG2a
Clonality	Monoclonal
Specificity	Anti-mouse Tim-3 (T cell immunoglobulin domain, mucin domain 3) monoclonal antibody reacts with mouse Tim-3.
Formulation	PBS containing 0.02% sodium azide (NaN39 as preservative and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL. Label: Biotin State: Liquid purified IgG fraction
Concentration	lot specific
Conjugation	Biotin
Storage	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Stability	Shelf life: one year from despatch.
Gene Name	hepatitis A virus cellular receptor 2
Database Link	Entrez Gene 171285 Mouse UniProt ID Q8VIM0
Background	This 281 amino acid type 1 transmembrane protein contains an immunoglobulin and mucin-like domain in its extra-cellular portion and a tyrosine phosphorylation motif in its cytoplasmic portion. Tim-3 is a member of the immunoglobulin super-family and is expressed on Th1 lymphocytes and CD11b+ macrophages. Tim-3 is a T helper type 1 (TH1)-specific molecule that regulates TH1 mediated auto and alloimmune responses and the induction of peripheral immunological tolerance.
Synonyms	TIMD-3, TIM3, TIM-3, T-cell membrane protein 3, HAVCR-2
Reference Data