Clinisciences > HSPD1 Antibody
HSPD1 Antibody
Referência OAMA00293
Tamanho : 1MG
Marca : Aviva Systems Biology
HSPD1 Antibody (OAMA00293)
| Datasheets/Manuals | Printable datasheet for HSPD1 Antibody (OAMA00293) |
|---|
| Predicted Species Reactivity | Mycobacterium tuberculosis |
|---|---|
| Product Format | Purified, Liquid |
| Clonality | Monoclonal |
| Clone | BDI578 |
| Isotype | IgG2a |
| Host | Mouse. Source: Ascites |
| Application | EIA,WB |
| :: | Buffer: 0.01M PBS, pH 7.2 Product contains no stabilizing proteins. Preservative: 0.1% Sodium azide Important Note: Centrifuge before opening to ensure complete recovery of vial contents. Warnings: This product contains sodium azide, which has been classified as Xn (Harmful) in European Directive 67/548/EEC in the concentration range of 0.1 - 1.0 %. When disposing of this reagent through lead or copper plumbing, flush with copious volumes |
| Reconstitution and Storage | Upon receipt, aliquot and store at -20C. Avoid multiple freeze/thaw cycles. |
| Purification | Purified |
| Specificity | Mycobacterium tuberculosis, Hsp65 Reactive with Hsp65 (GroEL) of M. tuberculosis. Does not react with M. bovis, M. avium, M. phlei, M. parafortuitum, Rhodococcus sp., B. subtilis, S. pneumoniae, and E. coli |
| Purity | >90% pure. Protein A chromatography |
| Application Data | Immunogen: Purified protein derivative (PPD) Affinity Constant: Not determined |
| Gene Symbol | HSPD1 |
|---|---|
| Gene Full Name | 60 kDa heat shock protein, mitochondrial |
| Alias Symbols | HLD4, CPN60, GROEL, HSP60, HSP65, SPG13, HSP-60, HuCHA60 |
| NCBI Gene Id | 3329 |
| Protein Name | 60 kDa heat shock protein, mitochondrial |
| Uniprot ID | P10809 |
| Protein Accession # | NP_002147.2; NP_955472.1; XP_005246575.1 |
| Nucleotide Accession # | NM_002156.4; NM_199440.1; XM_005246518.2 |
Protein interactions
| Name | # of Products |
|---|---|
| ALDH2 | 23 |
| ALK | 102 |
| AMFR | 164 |
| APP | 257 |
| BAK1 | 70 |
| CA2 | 30 |
| CASP | 8 |
| CASP3 | 324 |
| CASP9 | 126 |
| CD4 | 497 |
| CDK9 | 249 |
| DHFR | 16 |
| EBNA-LP | 380 |
| FHIT | 16 |
| HDAC5 | 906 |
| HIST2H2BE | 111 |
| HNRNPH1 | 126 |
| HSPD1 | 127 |
| HSPE1 | 25 |
| ICT1 | 287 |
| ITGA3 | 86 |
| ITGB1 | 292 |
| MAPK6 | 386 |
| MYC | 816 |
| PCK1 | 184 |
| PPP2R1A | 165 |
| PPP2R1B | 151 |
| PPP2R2C | 42 |
| PRKACA | 388 |
| PRNP | 113 |
| PSMA3 | 438 |
| RASA1 | 218 |
| RPAP1 | 52 |
| SIRT1 | 310 |
| SIRT3 | 58 |
| SPG20 | 67 |
| SRRM2 | 277 |
| STUB1 | 399 |
| SUMO4 | 252 |
| TLR1 | 73 |
| UBC | 7030 |
| YWHAG | 596 |
Biological pathways
| Name | # of Products |
|---|---|
| Activation of cysteine-type endopeptidase activity involved in apoptotic process | 193 |
| B cell cytokine production | 8 |
| B cell proliferation | 243 |
| Chaperone-mediated protein complex assembly | 17 |
| De novo protein folding | 14 |
| Interspecies interaction between organisms | 817 |
| Isotype switching to IgG isotypes | 8 |
| MyD88-dependent toll-like receptor signaling pathway | 331 |
| Negative regulation of apoptotic process | 538 |
| Positive regulation of apoptotic process | 225 |
| Positive regulation of interferon-alpha production | 52 |
| Positive regulation of interferon-gamma production | 108 |
| Positive regulation of interleukin-10 production | 69 |
| Positive regulation of interleukin-12 production | 171 |
| Positive regulation of interleukin-6 production | 149 |
| Positive regulation of macrophage activation | 30 |
| Positive regulation of T cell activation | 121 |
| Positive regulation of T cell mediated immune response to tumor cell | 12 |
| Protein maturation | 17 |
| Protein refolding | 34 |
| Protein stabilization | 177 |
| Response to unfolded protein | 117 |
| T cell activation | 158 |
Biological process
| Name | # of Products |
|---|---|
| Activation of cysteine-type endopeptidase activity involved in apoptotic process | 100 |
| ATP catabolic process | 92 |
| B cell activation | 26 |
| B cell cytokine production | 2 |
| B cell proliferation | 22 |
| Cell death | 133 |
| Chaperone-mediated protein complex assembly | 10 |
| De novo protein folding | 4 |
| Interspecies interaction between organisms | 281 |
| Isotype switching to IgG isotypes | 2 |
| MyD88-dependent toll-like receptor signaling pathway | 65 |
| Negative regulation of apoptotic process | 356 |
| Positive regulation of apoptotic process | 239 |
| Positive regulation of interferon-alpha production | 11 |
| Positive regulation of interferon-gamma production | 61 |
| Positive regulation of interleukin-10 production | 32 |
| Positive regulation of interleukin-12 production | 39 |
| Positive regulation of interleukin-6 production | 63 |
| Positive regulation of macrophage activation | 18 |
| Positive regulation of T cell activation | 28 |
| Positive regulation of T cell mediated immune response to tumor cell | 3 |
| Protein maturation | 8 |
| Protein refolding | 11 |
| Protein stabilization | 64 |
| Response to unfolded protein | 47 |
| T cell activation | 68 |
Cellular components
| Name | # of Products |
|---|---|
| Cell surface | 369 |
| Coated pit | 38 |
| Coated vesicle | 2 |
| Cyclin-dependent protein kinase activating kinase holoenzyme complex | 6 |
| Cytoplasm | 4549 |
| Cytosol | 1868 |
| Early endosome | 107 |
| Extracellular space | 884 |
| Lipopolysaccharide receptor complex | 5 |
| Mitochon | 2 |
| Mitochondrial inner membrane | 251 |
| Mitochondrial matrix | 185 |
Protein function
| Name | # of Products |
|---|---|
| ATP binding | 2814 |
| ATPase activity | 285 |
| Cell surface binding | 163 |
| Chaperone binding | 213 |
| DNA replication origin binding | 28 |
| Lipopolysaccharide binding | 102 |
| Nucleotide binding | 3928 |
| P53 binding | 139 |
| Protein binding | 12191 |
| Single-stranded DNA binding | 136 |
| Unfolded protein binding | 252 |
Diseases
| Name | # of Products |
|---|---|
| Disease mutation | 5332 |
| Hereditary spastic paraplegia | 43 |
| Leukodystrophy | 62 |
| Neurodegeneration | 458 |
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