Human MMP-8 (Matrix Metalloproteinase 8) CLIA Kit
Referência MBS2530810-96
Tamanho : 96Tests
Marca : MyBiosource
MMP-8 (Matrix Metalloproteinase 8) (MMP-8) CLIA Kit for Human
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2530810Intended Uses: This CLIA kit applies to the in vitro quantitative determination of MMP-8 concentrations in serum, plasma and other biological fluids.Principle of the Assay: This kit uses Sandwich-CLIA as the method. The micro CLIA plate provided in this kit… More details
Product Overview
Online Datasheet in PDFProduct Name
MMP-8 (Matrix Metalloproteinase 8), CLIA Kit
Full Product Name
Human MMP-8 (Matrix Metalloproteinase 8) CLIA Kit
Product Gene Name
MMP-8 clia kit
Product Synonym Names
MMP8; CLG1; HNC; PMNL-CL; Neutrophil Collagenase
Species Reactivity
Human
Assay Type
Sandwich
Detection Range
31.25-2000pg/mL
Sensitivity
Min: 18.75pg/mL; Max: 2000pg/mL
Specificity
This kit recognizes natural and recombinant MMP-8. No significant cross-reactivity or interference between MMP-8 and analogues was observed.
Molecular Weight
53,412 Da
OMIM
120355
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of MMP-8 clia kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for MMP-8 purchase
MBS2530810 is a CLIA kit targeting MMP-8. Also known as Human MMP-8 (Matrix Metalloproteinase 8) CLIA Kit. Reactive in Human.
Additional Details
NCBI/Uniprot data below describe general gene information for MMP-8. It may not necessarily be applicable to this product.
NCBI Official Full Name
matrix metalloproteinase 8 (neutrophil collagenase)
NCBI Official Synonym Full Names
matrix metallopeptidase 8
NCBI Official Symbol
MMP8
NCBI Official Synonym Symbols
HNC; CLG1; MMP-8; PMNL-CL
UniProt Protein Name
Neutrophil collagenase
UniProt Synonym Protein Names
Matrix metalloproteinase-8; MMP-8; PMNL collagenase; PMNL-CL
UniProt Gene Name
MMP8
UniProt Synonym Gene Names
CLG1; MMP-8; PMNL-CL
UniProt Entry Name
MMP8_HUMAN
NCBI Protein Information
neutrophil collagenase
NCBI Summary for MMP-8
This gene encodes a member of the matrix metalloproteinase (MMP) family of proteins. These proteins are involved in the breakdown of extracellular matrix in embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Proteolysis at different sites on this protein results in multiple active forms of the enzyme with distinct N-termini. This protein functions in the degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
Show more UniProt Comments for MMP-8
MMP8: Can degrade fibrillar type I, II, and III collagens. Belongs to the peptidase M10A family.
Protein type: Secreted; Secreted, signal peptide; Protease; EC 3.4.24.34
Chromosomal Location of Human Ortholog: 11q22.3
Cellular Component: extracellular space; proteinaceous extracellular matrix; extracellular region
Molecular Function: zinc ion binding; metalloendopeptidase activity; serine-type endopeptidase activity; calcium ion binding
Biological Process: collagen catabolic process; extracellular matrix disassembly; extracellular matrix organization and biogenesis; proteolysis
Show more Protein type: Secreted; Secreted, signal peptide; Protease; EC 3.4.24.34
Chromosomal Location of Human Ortholog: 11q22.3
Cellular Component: extracellular space; proteinaceous extracellular matrix; extracellular region
Molecular Function: zinc ion binding; metalloendopeptidase activity; serine-type endopeptidase activity; calcium ion binding
Biological Process: collagen catabolic process; extracellular matrix disassembly; extracellular matrix organization and biogenesis; proteolysis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with MMP-8 clia kit
| Reference Product | PubMed Publications |
|---|---|
| MMP9 clia kit | >64 publications with MMP-8 and MMP9 |
| MMP2 clia kit | >50 publications with MMP-8 and MMP2 |
| MMP14 clia kit | >17 publications with MMP-8 and MMP14 |
| TIMP2 clia kit | >13 publications with MMP-8 and TIMP2 |
| MMP11 clia kit | >5 publications with MMP-8 and MMP11 |
| MMP15 clia kit | >3 publications with MMP-8 and MMP15 |
| MMP19 clia kit | >1 publications with MMP-8 and MMP19 |
| ELANE clia kit | >1 publications with MMP-8 and ELANE |
Pathways associated with MMP-8 clia kit
| Products by Pathway | Pathway Diagram |
|---|---|
| Activation Of Matrix Metalloproteinases Pathway antibodies | Activation Of Matrix Metalloproteinases Pathway Diagram |
| Collagen Degradation Pathway antibodies | Collagen Degradation Pathway Diagram |
| Degradation Of The Extracellular Matrix Pathway antibodies | Degradation Of The Extracellular Matrix Pathway Diagram |
| Extracellular Matrix Organization Pathway antibodies | Extracellular Matrix Organization Pathway Diagram |
| Matrix Metalloproteinases Pathway antibodies | Matrix Metalloproteinases Pathway Diagram |
Organs/Tissues associated with MMP-8 clia kit
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Blood Antibodies | >95 publications with MMP-8 and Blood |
| Connective Tissue Antibodies | >16 publications with MMP-8 and Connective Tissue |
| Skin Antibodies | >14 publications with MMP-8 and Skin |
| Liver Antibodies | >11 publications with MMP-8 and Liver |
| Bone Marrow Antibodies | >9 publications with MMP-8 and Bone Marrow |
| Thymus Antibodies | >1 publications with MMP-8 and Thymus |