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> Integrin alpha V beta 6 Protein, Human, Recombinant (Avi & His)

Integrin alpha V beta 6 Protein, Human, Recombinant (Avi & His)

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Referência NB-64-128417-5ug

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Integrin alpha V beta 6 Protein, Human, Recombinant (Avi & His)

(Synonyms: ITGAV & ITGB6, integrin, α5 (fibronectin receptor, α polypeptide), integrin, alpha 5 (fibronectin receptor, alpha polypeptide), Integrin α V β 6, Integrin alpha V β6) Copy Product Info

Synonyms: ITGAV & ITGB6, integrin, α5 (fibronectin receptor, α polypeptide), integrin, alpha 5 (fibronectin receptor, alpha polypeptide), Integrin α V β 6, Integrin alpha V β6

Catalog No. TMPY-03878U Copy Product Info
Integrin alpha V beta 6 Protein, Human, Recombinant (Avi & His) is expressed in HEK293 Cells. The accession number is P06756-1(ITGAV)&P18564-1(ITGB6).
For research use only—not for human use. No sales to individuals. Use as intended only.

Product Information

Bioactivity
Bioactivity
Immobilized Human ITGAV&ITGB6, His Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Biotinylated Human Latent TGF beta 1, His Tag with the EC50 of 0.49 μg/ml determined by ELISA.
Description
Integrin alpha V beta 6 Protein, Human, Recombinant (Avi & His) is expressed in HEK293 Cells. The accession number is P06756-1(ITGAV)&P18564-1(ITGB6).
Species
Human
Expression System
HEK293 Cells
TagC-His-Avi
Accession NumberP06756-1(ITGAV)&P18564-1(ITGB6)
ConstructionPhe31-Val992(ITGAV) acidic tail & Gly22-Asn707(ITGB6) basic tail
Protein Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
ReconstitutionReconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
SynonymsITGAV & ITGB6, integrin, α5 (fibronectin receptor, α polypeptide), integrin, alpha 5 (fibronectin receptor, alpha polypeptide), Integrin α V β 6, Integrin alpha V β6
Research Background
ITGAV&ITGB6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of integrin alpha-V/beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion. ITGAV&ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1.
Chemical Properties
Molecular Weight114 kDa (ITGAV) & 79.1 kDa (ITGB6) (Predicted); 90-150 kDa (Due to glycosylation)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

TMPY-03878integrin, α 5integrin, alpha 5integrin, a 5fibronectin receptor, α polypeptidefibronectin receptor, alpha polypeptidefibronectin receptor, a polypeptide
Related Tags: Integrin alpha V beta 6 Protein, Human, Recombinant (Avi & His) chemical structure | Integrin alpha V beta 6 Protein, Human, Recombinant (Avi & His) molecular weight