ITGB4 Antibody
Referência OACA10166-50UG
Tamanho : 50ug
Marca : Aviva Systems Biology
ITGB4 Antibody (OACA10166)
| Datasheets/Manuals | Printable datasheet for ITGB4 Antibody (OACA10166) |
|---|
| Predicted Species Reactivity | Human|Mouse |
|---|---|
| Product Format | Liquid |
| Clonality | Polyclonal |
| Isotype | IgG |
| Host | Rabbit |
| Conjugation | Unconjugated |
| Application | ELISA|IF|IHC|WB |
| Reconstitution and Storage | -20°C or -80°C |
| Immunogen | Recombinant Human Integrin beta-4 protein (1401-1533AA) |
| Purification | Protein G Purified |
| Preservative | 0.03% Proclin 300 |
| Formulation | 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purity | >95% |
| Gene Symbol | ITGB4 |
|---|---|
| Gene Full Name | integrin subunit beta 4 |
| Alias Symbols | CD104, CD104 antigen, GP150, integrin beta-4. |
| NCBI Gene Id | 3691 |
| Protein Name | Integrin beta-4 |
| Description of Target | Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed:20682778). ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed:22351760). ITGA6:ITGB4 binds to IGF2 and this binding is essential for IGF2 signaling (PubMed:28873464). |
| Uniprot ID | P16144 |
| Protein Accession # | NP_000204 |
| Nucleotide Accession # | NM_000213 |
