Reagentes e instrumentos para imunologia, biologia celular e biologia molecular.

Methacrylamide [79-39-0]

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Referência NB-64-67427-5g

Tamanho : 5g

Marca : Neo Biotech

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Methacrylamide

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Synonyms:

Catalog No. TN7113 Copy Product Info

Purity: 99.7%

Methacrylamide is a natural product with dyeing property.

Cas No. 79-39-0

For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:99.7%

Appearance:Solid

Color:White

Product Introduction

Methacrylamide AI Summary

Methacrylamide exhibits significant inhibitory activity against multiple targets. Notably, it inhibits horse liver alcohol dehydrogenase with a Ki value of 954992.59 nM. Additionally, it shows inhibitory activity against Tyrosyl-DNA Phosphodiesterase (TDP1) with a potency of 14125.4 nM, and it inhibits Human Apurinic/apyrimidinic Endonuclease 1 (APE1) with a potency of 281.8 nM. Furthermore, Methacrylamide demonstrates cytotoxic activity in the MultiTox-Fluor Cytotoxicity Assay with a potency of 25118.9 nM. The compound also has a partition coefficient (logP) of -0.71..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Methacrylamide is a natural product with dyeing property.

Chemical Properties

Molecular Weight	85.1
Formula	C₄H₇NO
Cas No.	79-39-0
Smiles	CC(=C)C(N)=O
Relative Density.	1.14 g/cm³. Temperature:25 °C.

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 200 mg/mL (2350.18 mM), Sonication is recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	11.7509 mL	58.7544 mL	117.5088 mL	587.5441 mL
5 mM	2.3502 mL	11.7509 mL	23.5018 mL	117.5088 mL
10 mM	1.1751 mL	5.8754 mL	11.7509 mL	58.7544 mL
20 mM	0.5875 mL	2.9377 mL	5.8754 mL	29.3772 mL
50 mM	0.2350 mL	1.1751 mL	2.3502 mL	11.7509 mL
100 mM	0.1175 mL	0.5875 mL	1.1751 mL	5.8754 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

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Keywords

Methacrylamide

Related Tags: Methacrylamide chemical structure | Methacrylamide formula | Methacrylamide molecular weight