Mouse Glutamate Dehydrogenase 1 (GDH) Antibody Pair Kit (with Standard)

Referência MBS2098734-10x96

Tamanho : 10x96Tests

Marca : MyBiosource


Glutamate Dehydrogenase 1 (GDH) Antibody Pair Kit for Mouse

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2098734
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MBS2098734 is an antibody pair kit targeting GDH. Also known as Mouse Glutamate Dehydrogenase 1 (GDH) Antibody Pair Kit (with Standard). Reactive in Mouse. More details

Product Overview

Online Datasheet in PDF
Product Name
Glutamate Dehydrogenase 1 (GDH), Antibody Pair Kit
Full Product Name
Mouse Glutamate Dehydrogenase 1 (GDH) Antibody Pair Kit (with Standard)
Product Gene Name
GDH antibody pair kit
Product Synonym Names
GLUD1; Glutamate dehydrogenase 1, mitochondrial
Species Reactivity
Mouse
Samples
Serum, Plasma, Tissue Homogenates and Other Biological Fluids
Detection Range
0.312-20ng/mL
Molecular Weight
46,575 Da
OMIM
X07674 mRNA
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Standard
Recombinant GDH (Lyophilized, 1 vial-10ug)
Capture Antibody
Rabbit polyclonal antibody (Liquid, 1 vial-400mug/800muL)
Detection Antibody
Biotinylated Rabbit polyclonal antibody (Liquid, 1 vial-100mug/500muL)
Producte Usage
Raw materials can be used for preparation of 5x96T or 10x96T ELISA Kits.
Antibody Support Pack
Antibody Support Pack (Buffer Pack) is sold separately as catalog #MBS2090685

Product Categories/Family for GDH antibody pair kit

Enzyme & Kinase; Endocrinology; Neuroscience
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for GDH antibody pair kit
ELISA (EIA), Chemiluminescence Immunoassays (CLIA), ELISPOT, Luminex

Other Notes

Small volumes of GDH antibody pair kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GDH. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Glutamate dehydrogenase 1
NCBI Official Synonym Full Names
glutamate dehydrogenase 1
NCBI Official Symbol
GLUD1
NCBI Official Synonym Symbols
GDH; GDH1; GLUD
UniProt Protein Name
Glutamate dehydrogenase 1, mitochondrial
Protein Family
Glutamate dehydrogenase
UniProt Gene Name
GLUD1
UniProt Synonym Gene Names
GLUD; GDH 1
NCBI Protein Information
glutamate dehydrogenase 1, mitochondrial

NCBI Summary for GDH

This gene encodes glutamate dehydrogenase, which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid-induced insulin secretion. It is allosterically activated by ADP and inhibited by GTP and ATP. Activating mutations in this gene are a common cause of congenital hyperinsulinism. Alternative splicing of this gene results in multiple transcript variants. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Related pseudogenes have been identified on chromosomes 10, 18 and X. [provided by RefSeq, Jan 2016]
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UniProt Comments for GDH

Mitochondrial glutamate dehydrogenase that converts L-glutamate into alpha-ketoglutarate. Plays a key role in glutamine anaplerosis by producing alpha-ketoglutarate, an important intermediate in the tricarboxylic acid cycle. May be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with GDH antibody pair kit

 Reference Product  PubMed Publications
 CPS1 antibody pair kit  >4 publications with GDH and CPS1
 GOT1 antibody pair kit  >4 publications with GDH and GOT1
 GLUL antibody pair kit  >4 publications with GDH and GLUL
 IDH1 antibody pair kit  >1 publications with GDH and IDH1
 GPT2 antibody pair kit  >1 publications with GDH and GPT2
 GOT2 antibody pair kit  >1 publications with GDH and GOT2

Pathways associated with GDH antibody pair kit

 Products by Pathway  Pathway Diagram
 Alanine, Aspartate And Glutamate Metabolism Pathway antibodies  Alanine, Aspartate And Glutamate Metabolism Pathway Diagram
 Alanine, Aspartate And Glutamate Metabolism Pathway antibodies  Alanine, Aspartate And Glutamate Metabolism Pathway Diagram
 Amino Acid Metabolism Pathway antibodies  Amino Acid Metabolism Pathway Diagram
 Amino Acid Synthesis And Interconversion (transamination) Pathway antibodies  Amino Acid Synthesis And Interconversion (transamination) Pathway Diagram
 Arginine Biosynthesis Pathway antibodies  Arginine Biosynthesis Pathway Diagram
 Arginine Biosynthesis Pathway antibodies  Arginine Biosynthesis Pathway Diagram
 Carbon Metabolism Pathway antibodies  Carbon Metabolism Pathway Diagram
 Carbon Metabolism Pathway antibodies  Carbon Metabolism Pathway Diagram
 D-Glutamine And D-glutamate Metabolism Pathway antibodies  D-Glutamine And D-glutamate Metabolism Pathway Diagram
 D-Glutamine And D-glutamate Metabolism Pathway antibodies  D-Glutamine And D-glutamate Metabolism Pathway Diagram

Diseases associated with GDH antibody pair kit

 Disease Name  Pubmed Publications
 Hyperinsulinism Antibodies  >79 publications with GDH and Hyperinsulinism
 Hyperammonemia Antibodies  >36 publications with GDH and Hyperammonemia
 Seizures Antibodies  >18 publications with GDH and Seizures
 Hyperinsulinemic hypoglycemia, familial, 6 Antibodies  >10 publications with GDH and Hyperinsulinemic hypoglycemia, familial, 6
 Liver Diseases Antibodies  >7 publications with GDH and Liver Diseases
 Hyperplasia Antibodies  >5 publications with GDH and Hyperplasia
 Inflammation Antibodies  >4 publications with GDH and Inflammation
 Movement Disorders Antibodies  >4 publications with GDH and Movement Disorders
 Poisoning Antibodies  >4 publications with GDH and Poisoning
 Necrosis Antibodies  >3 publications with GDH and Necrosis

Organs/Tissues associated with GDH antibody pair kit

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >72 publications with GDH and Brain
 Blood Antibodies  >32 publications with GDH and Blood
 Pancreas Antibodies  >24 publications with GDH and Pancreas
 Liver Antibodies  >21 publications with GDH and Liver
 Nerve Antibodies  >18 publications with GDH and Nerve
 Testis Antibodies  >9 publications with GDH and Testis
 Kidney Antibodies  >7 publications with GDH and Kidney
 Placenta Antibodies  >4 publications with GDH and Placenta
 Embryonic Tissue Antibodies  >3 publications with GDH and Embryonic Tissue
 Vascular Antibodies  >2 publications with GDH and Vascular