Mouse Serum Albumin
Referência MBS717450-100mg
Tamanho : 100mg
Marca : MyBiosource
Serum Albumin (ALB) Mouse Native Protein
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS717450Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in… More details
Product Overview
Online Datasheet in PDFProduct Name
Serum Albumin, Native Protein
Full Product Name
Mouse Serum Albumin
Product Gene Name
ALB native protein
Host
Purified from Mouse Serum
Form/Format
Liquid
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Preparation and Storage
Aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze / thaw cycles.
Applications Tested/Suitable for ALB native protein
ELISA (EIA), Western Blot (WB)
Other Notes
Small volumes of ALB native protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for ALB purchase
MBS717450 is a native protein targeting ALB. Also known as Mouse Serum Albumin. Host: Purified from Mouse Serum.
Additional Details
NCBI/Uniprot data below describe general gene information for ALB. It may not necessarily be applicable to this product.
NCBI Official Full Name
serum albumin preproprotein
NCBI Official Synonym Full Names
albumin
NCBI Official Symbol
ALB
NCBI Official Synonym Symbols
PRO0883; PRO0903; PRO1341
UniProt Protein Name
Serum albumin
Protein Family
Serum albumin
UniProt Gene Name
ALB
UniProt Entry Name
ALBU_HUMAN
NCBI Protein Information
serum albumin; albumin (32 AA); albumin (AA 34); growth-inhibiting protein 20; cell growth inhibiting protein 42
NCBI Summary for ALB
Albumin is a soluble, monomeric protein which comprises about one-half of the blood serum protein. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Albumin is a globular unglycosylated serum protein of molecular weight 65,000. Albumin is synthesized in the liver as preproalbumin which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted albumin. [provided by RefSeq, Jul 2008]
Show more UniProt Comments for ALB
Function: Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca2+, Na+, K+, fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc. Ref.33
Subcellular location: Secreted.
Tissue specificity: Plasma. Ref.35
Post-translational modification: Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606.Glycated in diabetic patients.Phosphorylation sites are present in the extracelllular medium.Acetylated on Lys-223 by acetylsalicylic acid.
Polymorphism: A variant structure of albumin could lead to increased binding of zinc resulting in an asymptomatic augmentation of zinc concentration in the blood. The sequence shown is that of variant albumin A.
Involvement in disease: Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [
MIM:103600]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T4. It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population. Ref.64 Ref.65 Ref.66 Ref.67
Sequence similarities: Belongs to the ALB/AFP/VDB family.Contains 3 albumin domains.
Caution: A peptide arising from positions 166 to 174 was originally (Ref.23 and Ref.24) termed neurotensin-related peptide (NRP) or kinetensin and was thought to regulates fat digestion, lipid absorption, and blood flow.
Sequence caution: The sequence AAF22034.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.The sequence AAF69644.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.The sequence AAG35503.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.
Show more Subcellular location: Secreted.
Tissue specificity: Plasma. Ref.35
Post-translational modification: Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606.Glycated in diabetic patients.Phosphorylation sites are present in the extracelllular medium.Acetylated on Lys-223 by acetylsalicylic acid.
Polymorphism: A variant structure of albumin could lead to increased binding of zinc resulting in an asymptomatic augmentation of zinc concentration in the blood. The sequence shown is that of variant albumin A.
Involvement in disease: Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [
MIM:103600]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T4. It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population. Ref.64 Ref.65 Ref.66 Ref.67
Sequence similarities: Belongs to the ALB/AFP/VDB family.Contains 3 albumin domains.
Caution: A peptide arising from positions 166 to 174 was originally (Ref.23 and Ref.24) termed neurotensin-related peptide (NRP) or kinetensin and was thought to regulates fat digestion, lipid absorption, and blood flow.
Sequence caution: The sequence AAF22034.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.The sequence AAF69644.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.The sequence AAG35503.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.
Research Articles on ALB
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with ALB native protein
| Reference Product | PubMed Publications |
|---|---|
| APOE native protein | >4 publications with ALB and APOE |
| HNF1A native protein | >3 publications with ALB and HNF1A |
| AGA native protein | >2 publications with ALB and AGA |
| RBP4 native protein | >1 publications with ALB and RBP4 |
Pathways associated with ALB native protein
| Products by Pathway | Pathway Diagram |
|---|---|
| Bile Acid And Bile Salt Metabolism Pathway antibodies | Bile Acid And Bile Salt Metabolism Pathway Diagram |
| FOXA2 And FOXA3 Transcription Factor Networks Pathway antibodies | FOXA2 And FOXA3 Transcription Factor Networks Pathway Diagram |
| HDL-mediated Lipid Transport Pathway antibodies | HDL-mediated Lipid Transport Pathway Diagram |
| Hemostasis Pathway antibodies | Hemostasis Pathway Diagram |
| Lipid Digestion, Mobilization, And Transport Pathway antibodies | Lipid Digestion, Mobilization, And Transport Pathway Diagram |
| Lipoprotein Metabolism Pathway antibodies | Lipoprotein Metabolism Pathway Diagram |
| Metabolism Pathway antibodies | Metabolism Pathway Diagram |
| Metabolism Of Lipids And Lipoproteins Pathway antibodies | Metabolism Of Lipids And Lipoproteins Pathway Diagram |
| Platelet Activation, Signaling And Aggregation Pathway antibodies | Platelet Activation, Signaling And Aggregation Pathway Diagram |
| Platelet Degranulation Pathway antibodies | Platelet Degranulation Pathway Diagram |
Diseases associated with ALB native protein
| Disease Name | Pubmed Publications |
|---|---|
| Liver Diseases Antibodies | >355 publications with ALB and Liver Diseases |
| Neoplasms Antibodies | >256 publications with ALB and Neoplasms |
| Kidney Diseases Antibodies | >222 publications with ALB and Kidney Diseases |
| Proteinuria Antibodies | >163 publications with ALB and Proteinuria |
| Cardiovascular Diseases Antibodies | >152 publications with ALB and Cardiovascular Diseases |
| Disease Models, Animal Antibodies | >147 publications with ALB and Disease Models, Animal |
| Hepatitis Antibodies | >146 publications with ALB and Hepatitis |
| Inflammation Antibodies | >134 publications with ALB and Inflammation |
| Nervous System Diseases Antibodies | >130 publications with ALB and Nervous System Diseases |
| Liver Neoplasms Antibodies | >127 publications with ALB and Liver Neoplasms |
Organs/Tissues associated with ALB native protein
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Blood Antibodies | >1137 publications with ALB and Blood |
| Liver Antibodies | >620 publications with ALB and Liver |
| Kidney Antibodies | >294 publications with ALB and Kidney |
| Lung Antibodies | >114 publications with ALB and Lung |
| Heart Antibodies | >93 publications with ALB and Heart |
| Spleen Antibodies | >44 publications with ALB and Spleen |
| Mixed Antibodies | >43 publications with ALB and Mixed |