Myeloperoxidase assay kit
Referência MBS2540454-5x100
Tamanho : 5x100Assays
Marca : MyBiosource
Myeloperoxidase (MPO) Assay Kit
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2540454Principle of the Assay: Myeloperoxidase reduces hydrogen peroxide to a complex. The complex react with o-dianisidine (as hydrogen donor) to produce a yellow product which has a maximum absorption peak at 460 nm. The activity of MPO can be calculated… More details
Product Overview
Online Datasheet in PDFProduct Name
Myeloperoxidase (MPO), Assay Kit
Full Product Name
Myeloperoxidase assay kit
Product Gene Name
MPO assay kit
Samples
Serum, plasma, milk, animal tissue, cells and other samples
Detection Range
16.95-3349 U/L
Sensitivity
16.95 U/L
Preparation and Storage
Store at 2-8 degree C. Valid for 12 months
Inter-assay Precision
Inter-assay CV is 9.8%.
Intra-assay Precision
Intra-assay CV is 4.5 %.
Molecular Weight
87,248 Da
OMIM
J02694 mRNA
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of MPO assay kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for MPO purchase
MBS2540454 is an assay kit targeting MPO. Also known as Myeloperoxidase assay kit.
Additional Details
NCBI/Uniprot data below describe general gene information for MPO. It may not necessarily be applicable to this product.
NCBI Official Full Name
myeloperoxidase
NCBI Official Synonym Full Names
myeloperoxidase
NCBI Official Symbol
MPO
UniProt Protein Name
Myeloperoxidase
Protein Family
Myeloperoxidase
UniProt Gene Name
MPO
UniProt Synonym Gene Names
MPO
UniProt Entry Name
PERM_HUMAN
NCBI Protein Information
myeloperoxidase
NCBI Summary for MPO
Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils. [provided by RefSeq, Nov 2014]
Show more UniProt Comments for MPO
MPO: Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity. Homodimer; disulfide-linked. Each monomer consists of a light and a heavy chain. Belongs to the peroxidase family. XPO subfamily. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 1.11.2.2; Oxidoreductase
Chromosomal Location of Human Ortholog: 17q23.1
Cellular Component: azurophil granule; extracellular space; lysosome; nucleus; secretory granule
Molecular Function: chromatin binding; heparin binding; peroxidase activity
Biological Process: defense response; defense response to bacterium; hydrogen peroxide catabolic process; negative regulation of apoptosis; response to oxidative stress
Disease: Alzheimer Disease; Myeloperoxidase Deficiency
Show more Protein type: EC 1.11.2.2; Oxidoreductase
Chromosomal Location of Human Ortholog: 17q23.1
Cellular Component: azurophil granule; extracellular space; lysosome; nucleus; secretory granule
Molecular Function: chromatin binding; heparin binding; peroxidase activity
Biological Process: defense response; defense response to bacterium; hydrogen peroxide catabolic process; negative regulation of apoptosis; response to oxidative stress
Disease: Alzheimer Disease; Myeloperoxidase Deficiency
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with MPO assay kit
| Reference Product | PubMed Publications |
|---|---|
| PTGS1 assay kit | >35 publications with MPO and PTGS1 |
| MYB assay kit | >13 publications with MPO and MYB |
| JAK2 assay kit | >9 publications with MPO and JAK2 |
| IL23A assay kit | >1 publications with MPO and IL23A |
Pathways associated with MPO assay kit
| Products by Pathway | Pathway Diagram |
|---|---|
| Benzene Metabolism Pathway antibodies | Benzene Metabolism Pathway Diagram |
| C-MYB Transcription Factor Network Pathway antibodies | C-MYB Transcription Factor Network Pathway Diagram |
| Folate Metabolism Pathway antibodies | Folate Metabolism Pathway Diagram |
| IL23-mediated Signaling Events Pathway antibodies | IL23-mediated Signaling Events Pathway Diagram |
| Immune System Pathway antibodies | Immune System Pathway Diagram |
| Innate Immune System Pathway antibodies | Innate Immune System Pathway Diagram |
| Neutrophil Degranulation Pathway antibodies | Neutrophil Degranulation Pathway Diagram |
| Phagosome Pathway antibodies | Phagosome Pathway Diagram |
| Phagosome Pathway antibodies | Phagosome Pathway Diagram |
| Selenium Micronutrient Network Pathway antibodies | Selenium Micronutrient Network Pathway Diagram |
Diseases associated with MPO assay kit
| Disease Name | Pubmed Publications |
|---|---|
| Inflammation Antibodies | >3249 publications with MPO and Inflammation |
| Cardiovascular Diseases Antibodies | >2336 publications with MPO and Cardiovascular Diseases |
| Necrosis Antibodies | >1814 publications with MPO and Necrosis |
| Lung Diseases Antibodies | >1375 publications with MPO and Lung Diseases |
| Reperfusion Injury Antibodies | >943 publications with MPO and Reperfusion Injury |
| Colitis Antibodies | >802 publications with MPO and Colitis |
| Edema Antibodies | >726 publications with MPO and Edema |
| Kidney Diseases Antibodies | >719 publications with MPO and Kidney Diseases |
| Heart Diseases Antibodies | >525 publications with MPO and Heart Diseases |
| Hemorrhage Antibodies | >481 publications with MPO and Hemorrhage |
Organs/Tissues associated with MPO assay kit
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Blood Antibodies | >5562 publications with MPO and Blood |
| Lung Antibodies | >1725 publications with MPO and Lung |
| Kidney Antibodies | >845 publications with MPO and Kidney |
| Brain Antibodies | >694 publications with MPO and Brain |
| Bone Antibodies | >437 publications with MPO and Bone |
| Bone Marrow Antibodies | >337 publications with MPO and Bone Marrow |
| Eye Antibodies | >110 publications with MPO and Eye |
| Lymph Node Antibodies | >102 publications with MPO and Lymph Node |
| Thyroid Antibodies | >94 publications with MPO and Thyroid |
| Embryonic Tissue Antibodies | >48 publications with MPO and Embryonic Tissue |